Medication safety
The equivalence conversions, weight-based dosing and infusion-rate math you redo all the time, turned into tools you fill in to get the answer. Conversion factors are verified and computed locally — nothing is uploaded. Opioids include a cross-tolerance dose reduction; weight-based dosing includes dose caps.
💊 Opioid Equianalgesic Converter (OME)
Convert daily opioid doses between agents via oral morphine equivalents (OME), with an incomplete cross-tolerance reduction range.
💊 Benzodiazepine Equivalent Converter
Convert between benzodiazepines by diazepam equivalents, for switching and tapering (long-acting substitution for short-acting agents).
💉 Vancomycin Empiric Dosing
Empiric vancomycin loading dose, maintenance dose and interval by weight and creatinine clearance (AUC-guided; requires TDM).
💊 Acetaminophen (Paracetamol) Dose & Toxicity Threshold
Check acetaminophen daily/single-dose limits and whether an acute ingestion reaches the toxic threshold or warrants NAC.
💉 Aminoglycoside Empiric Dosing
Gentamicin/tobramycin/amikacin high-dose extended-interval (once-daily) empiric dosing by dosing weight and CrCl; requires TDM.
🫘 Renal Dose Adjustment Quick Reference
Quick reference for adjusting common renally-cleared drugs by renal function (CrCl/eGFR); not exhaustive — follow the latest product label.
📈 QT Prolongation Risk & High-Risk Drugs
Quick reference to high-risk drug classes, risk factors and management for QT prolongation / torsades (TdP); per-drug authoritative ratings at CredibleMeds.
🤰 Medication Use in Pregnancy — Reference
The former FDA letter categories (withdrawn 2015), the PLLR labelling rule, prescribing principles and authoritative resources; not a per-drug rating.
🚨 Pediatric Code (PALS) Dose Card
Weight-based PALS emergency drugs and electrical therapy doses (epinephrine/amiodarone/adenosine/atropine/defibrillation/fluids, etc.).
🎯 Therapeutic Drug Monitoring (TDM) Targets
Quick reference to target ranges, sampling timing and toxicity cues for commonly monitored drugs.
🫀 Hepatic Dose Adjustment Key Points
Adjustment and avoidance points for common drugs in hepatic impairment (Child-Pugh), by class; follow the product label.
🔗 Drug Interaction Key Points
Quick reference to mechanisms and typical combinations for high-frequency, dangerous drug interactions; check each pair in a professional interaction database.
🩸 Warfarin & INR Management
Target INR, high-INR/bleeding management (ACCP/CHEST), interactions and missed-dose points.
💉 Unfractionated Heparin (UFH) Weight-Based Dosing
Weight-based UFH IV loading dose and initial maintenance rate (Raschke nomogram), aPTT/anti-Xa guided.
🧂 Electrolyte Replacement Reference
Dose, route and rate-limit points for repleting potassium/magnesium/calcium/phosphate (sodium & free-water deficits are in the electrolyte/acid-base group).
🌉 Perioperative Anticoagulant/Antiplatelet Bridging
Warfarin bridging, DOAC interruption and resumption, and perioperative antiplatelet handling (CHEST 2022 / ACC / ASRA).
🩸 Perioperative / Stress Glycaemic Management
Inpatient/perioperative glucose targets, pre-op antidiabetic adjustment, steroid-induced hyperglycaemia and insulin-infusion points (ADA inpatient standards).
💊 Glucocorticoid Stress Dosing & Taper
Perioperative stress dosing (by surgical magnitude), adrenal crisis management and long-term steroid tapering (Endocrine Society / Woodcock 2020).
🧬 Tumour Lysis Syndrome (TLS) Prophylaxis
TLS risk stratification, prophylaxis (hydration/allopurinol/rasburicase), monitoring and the Cairo-Bishop definition.
🥗 Parenteral Nutrition Basic Formula Estimator
Estimate parenteral nutrition (PN) energy, protein, fluid, lipid and glucose targets by weight and stress state, with refeeding cautions (ASPEN).
💧 Fluids: Resuscitation & Rate Reference
Resuscitation volumes, maintenance fluids (links to calculators), fluid choice and rate-safety points (4-2-1 maintenance is in a dedicated tool).
☠️ Common Poisoning Antidotes Quick Reference
Specific antidotes and key doses/points for common poisonings; for life-threatening cases prioritise supportive care + poison-control contact.
🔄 Opioid / Benzodiazepine Antagonists
Dose, titration and risk points for naloxone (opioid) and flumazenil (benzodiazepine); supportive care is often safer.
🦠 Antibiotic Class Spectrum Quick Reference
Overview of the coverage (spectrum) of common antibiotic classes; empiric choice must factor in local susceptibility (e.g. CHINET), infection site and institutional protocol.
🫘 Antibiotic Renal Adjustment Key Points
Adjustment/avoidance points and key safety notes for common antibiotics by renal function (CrCl); includes a 'generally no adjustment' list — follow the label.
📐 Antibiotic PK/PD Dosing Strategy
PK/PD targets and optimised dosing strategies for time-dependent / concentration-dependent / AUC-type antibiotics (extended infusion, once-daily, etc.).
💉 IV Pump Rate Converter
Convert a drug amount, solution volume, weight and ordered dose into an IV pump rate (mL/h).
💊 Weight-Based Dose Calculator
Converts a mg/kg dose into a single dose with an optional per-dose cap; general/pediatric use.
💊 Glucocorticoid Equivalent Dose Conversion
Converts anti-inflammatory equivalent doses between different glucocorticoids.
Equivalence and dose-conversion values are taken from authoritative pharmacology sources and verified, but sources can differ slightly and results are estimates — individualize to the label, your formulary and the patient's hepatic/renal function. After opioid conversion, reduce by 25–50% for incomplete cross-tolerance; methadone, fentanyl patches and buprenorphine are excluded (specialist handling). All results are for licensed clinicians and do not replace clinical judgement.
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