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💊 Benzodiazepine Equivalent Converter

Convert between benzodiazepines by diazepam equivalents (Ashton values) to support switching and tapering. Instant, browser-side calculation.

Clinical takeaway

Equivalences differ widely between references — treat as an estimate only.

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When to use

Estimate equivalent doses when switching agents or substituting long-acting diazepam for short-acting drugs during a taper.

How it works

Diazepam equivalent = dose × (10 / agent equivalence); target = diazepam-eq × (target equivalence / 10). Ashton: diazepam 10 = alprazolam 0.5 = lorazepam 1 = clonazepam 0.5 = oxazepam 20 mg.

Key points

  • Equivalences differ widely between references — treat as an estimate only.
  • When tapering, long-acting diazepam smooths withdrawal from short-acting agents.
  • In hepatic impairment prefer oxazepam/lorazepam (not oxidatively metabolised).
  • Titrate gradually to response; never stop abruptly.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Frequently asked questions

What is Benzodiazepine Equivalent Converter?
Convert between benzodiazepines by diazepam equivalents (Ashton values) to support switching and tapering. Instant, browser-side calculation.
How is Benzodiazepine Equivalent Converter calculated? What is the core formula?
Diazepam equivalent = dose × (10 / agent equivalence); target = diazepam-eq × (target equivalence / 10). Ashton: diazepam 10 = alprazolam 0.5 = lorazepam 1 = clonazepam 0.5 = oxazepam 20 mg.
When is Benzodiazepine Equivalent Converter used?
Estimate equivalent doses when switching agents or substituting long-acting diazepam for short-acting drugs during a taper.
What are the key clinical points for Benzodiazepine Equivalent Converter?
Equivalences differ widely between references — treat as an estimate only. When tapering, long-acting diazepam smooths withdrawal from short-acting agents. In hepatic impairment prefer oxazepam/lorazepam (not oxidatively metabolised). Titrate gradually to response; never stop abruptly.
What are the limits and cautions when using Benzodiazepine Equivalent Converter?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

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