🤰 Medication Use in Pregnancy — Reference
Reference on medication use in pregnancy: the withdrawn FDA letter categories, the PLLR labelling rule, prescribing principles and authoritative resources. Browser-side.
Medication Use in Pregnancy — Reference
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When to use
Understand the labelling framework and where to find evidence-based per-drug guidance — not a per-drug rating itself.
How it works
PLLR (2015) replaced A/B/C/D/X letters with narrative sections: pregnancy, lactation, and females/males of reproductive potential.
Key points
- The old letter categories were misread as a risk ladder and are historical only.
- Weigh the risk of untreated maternal disease against the drug risk.
- Prefer well-evidenced agents at the lowest effective dose; organogenesis (≈ 3–8 weeks) is most sensitive.
- Consult MotherToBaby/LactMed and the latest label for specific drugs.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.