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🧂 Electrolyte Replacement Reference

Repletion doses, routes and rate ceilings for potassium, magnesium, calcium and phosphate. Browser-side reference.

Clinical takeaway

IV potassium too fast/concentrated risks arrhythmia — respect the ceiling.

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When to use

Bedside reminder of how much, by what route and how fast to replete each electrolyte. Sodium and free-water deficits are in the dedicated electrolyte tools.

How it works

K: oral 20–40 mmol, IV peripheral ≤ 10 mmol/h. Mg: MgSO4 1–2 g IV. Ca: gluconate 1–2 g IV slow. Phos: 0.08–0.16 mmol/kg over 2–6 h.

Key points

  • IV potassium too fast/concentrated risks arrhythmia — respect the ceiling.
  • Replace magnesium first; it underlies refractory hypokalaemia/hypocalcaemia.
  • Calcium gluconate is preferred over chloride peripherally.
  • Watch calcium-phosphate precipitation when co-infusing.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ElectrolyteHypokalaemia

Repletion pointsPotassium repletion

  • OralKCl 20–40 mmol, up to 100 mmol/day (mild-moderate, K 2.5–3.2)
  • IVPeripheral ≤ 10 mmol/h (concentration ≤ 30–40 mmol/L); central line + monitoring ≤ 20 mmol/h
  • KeyReplace magnesium concurrently (otherwise hard to correct); deficits often take days; monitor ECG and potassium
ElectrolyteHypophosphataemia

Repletion pointsPhosphate repletion

  • OralMild-moderate (1.0–2.4 mg/dL): oral phosphate salts
  • IVSevere (< 1.0) / symptomatic: sodium or potassium phosphate 0.08–0.16 mmol/kg over 2–6 h
  • MonitoringCalcium, renal function; risk of calcium-phosphate precipitation if co-infused with calcium

Frequently asked questions

What is Electrolyte Replacement Reference?
Repletion doses, routes and rate ceilings for potassium, magnesium, calcium and phosphate. Browser-side reference.
How is Electrolyte Replacement Reference calculated? What is the core formula?
K: oral 20–40 mmol, IV peripheral ≤ 10 mmol/h. Mg: MgSO4 1–2 g IV. Ca: gluconate 1–2 g IV slow. Phos: 0.08–0.16 mmol/kg over 2–6 h.
When is Electrolyte Replacement Reference used?
Bedside reminder of how much, by what route and how fast to replete each electrolyte. Sodium and free-water deficits are in the dedicated electrolyte tools.
What are the key clinical points for Electrolyte Replacement Reference?
IV potassium too fast/concentrated risks arrhythmia — respect the ceiling. Replace magnesium first; it underlies refractory hypokalaemia/hypocalcaemia. Calcium gluconate is preferred over chloride peripherally. Watch calcium-phosphate precipitation when co-infusing.
What are the limits and cautions when using Electrolyte Replacement Reference?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Electrolyte Replacement Reference calculated in practice? Can you show a worked example?
Inputs: Electrolyte Hypokalaemia → Result: Repletion points Potassium repletion(Oral: KCl 20–40 mmol, up to 100 mmol/day (mild-moderate, K 2.5–3.2), IV: Peripheral ≤ 10 mmol/h (concentration ≤ 30–40 mmol/L); central line + monitoring ≤ 20 mmol/h, Key: Replace magnesium concurrently (otherwise hard to correct); deficits often take days; monitor ECG and potassium) Inputs: Electrolyte Hypophosphataemia → Result: Repletion points Phosphate repletion(Oral: Mild-moderate (1.0–2.4 mg/dL): oral phosphate salts, IV: Severe (< 1.0) / symptomatic: sodium or potassium phosphate 0.08–0.16 mmol/kg over 2–6 h, Monitoring: Calcium, renal function; risk of calcium-phosphate precipitation if co-infused with calcium)

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