A clinician's
research + clinical toolkit
A full clinical-research workflow lab, 483+ bedside calculators and scores, and specialty-deep references. Free, mobile-friendly, computed locally — your data is never uploaded.
Clinical tools
All 483 tools →Turn guidelines into decisions
Enter the patient → risk stratification → thresholds → guideline recommendation, each with class of recommendation, level of evidence and source guideline. Computed locally; decision support for licensed clinicians.
Turn guidelines into pathways
From first contact to disposition, step through the decision tree: red / amber / green stratification → thresholds → guideline recommendation. Each pathway is checked against current guidelines, computed locally — for licensed clinicians.
Caustic (Strong Acid/Alkali) Ingestion — Management Pathway
The four nos (no emesis/lavage/neutralization/charcoal); airway first, early endoscopy grading at 12–24 h.
Fetal Encephalocele / Cranium Bifidum
Meningocele vs containing brain tissue; occipital most common; MRI assesses herniated contents + associated; check Meckel-Gruber.
Wernicke Encephalopathy — Management Pathway
Thiamine deficiency, the triad complete in only 16%; IV high-dose thiamine, before any glucose.
Pleural Effusion (Light's Criteria) — Pathway
Thoracentesis for protein/LDH, Light's criteria classify exudate/transudate; suspected hemothorax/empyema → emergency drainage.
Drowning — Management Pathway
The core injury is hypoxia, ventilation first; the Heimlich maneuver is not recommended; symptomatic/hypoxic → oxygen ± intubation, observe asymptomatic for 4–8 h.
Fetal Anemia (MCA-PSV)
MCA-PSV ≥1.5 MoM (Mari) predicts moderate-severe anemia; check alloimmunization/parvovirus/thalassemia; ≥1.5 or hydrops → intrauterine transfusion.
Malaria — Management Pathway
Confirm with blood film/RDT; triage by WHO severe criteria — IV artesunate for severe, oral ACT for uncomplicated.
Cervical Cancer · By FIGO Stage + Approach
IA1 conization/hysterectomy; IA2 modified radical + nodes; IB1-2/IIA1 radical hysterectomy (open superior to minimally invasive LACC); early small-volume fertility-sparing trachelectomy; locally advanced concurrent chemoradiation.
Statistics, ready to run
Fill in your data, get the result: agreement, diagnostic accuracy, survival, meta-analysis, modelling and more. Every tool computes locally in your browser — nothing is uploaded or stored.
Decision Curve Analysis (DCA)
Assess the clinical usefulness of a prediction model: net benefit across threshold probabilities, compared with the treat-all and treat-none reference lines, comparing several models at once, with an exportable curve. A standard for prediction-model papers.
Lin's CCC (Concordance Correlation)
Agreement between two measurement methods: CCC combines precision (Pearson r) and accuracy (bias-correction factor Cb), catching systematic bias that r alone misses — complementary to Bland–Altman. Gives CCC, r, Cb with 95% CI.
Win Ratio
Stratified composite-endpoint win ratio (Pocock 2012): compare time-to-event endpoints by priority, then a secondary continuous measure; pairwise treatment×control comparisons count wins/losses/ties, giving Win Ratio, Win Odds, Net Benefit and bootstrap 95% CI. Common in heart-failure/cardiovascular trials.
RR / OR / NNT Calculator
Enter a 2×2 table to compute relative risk RR, odds ratio OR, absolute risk difference ARD, relative risk reduction RRR and number needed to treat NNT, with 95% CIs for ratios and the risk difference. Common for interpreting cohort/case-control/RCT outcomes.
ROC Curve & Diagnostic Performance
Enter a gold standard and measured values to compute AUC (with 95% CI), draw the ROC curve, and give the optimal cutoff by Youden index with its sensitivity/specificity. A core tool for diagnostic imaging research.
Binary Logistic Regression
Analyze multiple factors' effects on a binary outcome, outputting each factor's OR, 95% CI, significance and model fit indices. A core method for clinical risk-factor analysis and prediction models.
Kappa Agreement
Inter-rater classification agreement: Cohen's Kappa (nominal) plus linear/quadratic weighted Kappa for ordinal grades, with a confusion matrix and agreement interpretation. Common for imaging-grade agreement.
NRI / IDI Reclassification
Incremental value of a new vs old prediction model: net reclassification improvement (NRI, continuous and categorical) and integrated discrimination improvement (IDI). When adding a new marker barely raises AUC, these quantify the reclassification and discrimination gain.