☠️ Common Poisoning Antidotes Quick Reference
Specific antidotes and key doses for common poisonings — acetaminophen, opioids, organophosphates, beta-blockers, CCBs, digoxin, toxic alcohols, cyanide and more. Browser-side.
Supportive care and decontamination come before the antidote.
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When to use
Rapid bedside reference for the targeted antidote. For life-threatening cases, prioritise airway/breathing/circulation, decontamination and a poison-control consult.
How it works
Examples: NAC for acetaminophen; naloxone for opioids; atropine + pralidoxime for organophosphates; fomepizole for toxic alcohols; hydroxocobalamin for cyanide.
Key points
- Supportive care and decontamination come before the antidote.
- Methylene blue and rasburicase are cautioned/contraindicated in G6PD deficiency.
- Long-acting toxins often outlast the antidote — repeat or infuse.
- Doses must be individualised to the toxin, amount and levels.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Toxin | Acetaminophen |
|---|
→AntidoteNAC (N-acetylcysteine)
- Dose：IV 150 mg/kg (1 h) → 50 mg/kg (4 h) → 100 mg/kg (16 h), total 300 mg/kg; or oral 140 + 70 ×17
- Key：Decide by the Rumack-Matthew line; see the 'Acetaminophen' tool
| Toxin | Local anaesthetic systemic toxicity |
|---|
→AntidoteLipid emulsion (20%)
- Dose：20% lipid emulsion 1.5 mL/kg bolus → 0.25 mL/kg/min infusion
- Key：Continue high-quality CPR; local anaesthetic systemic toxicity (LAST)
Frequently asked questions
- What is Common Poisoning Antidotes Quick Reference?
- Specific antidotes and key doses for common poisonings — acetaminophen, opioids, organophosphates, beta-blockers, CCBs, digoxin, toxic alcohols, cyanide and more. Browser-side.
- How is Common Poisoning Antidotes Quick Reference calculated? What is the core formula?
- Examples: NAC for acetaminophen; naloxone for opioids; atropine + pralidoxime for organophosphates; fomepizole for toxic alcohols; hydroxocobalamin for cyanide.
- When is Common Poisoning Antidotes Quick Reference used?
- Rapid bedside reference for the targeted antidote. For life-threatening cases, prioritise airway/breathing/circulation, decontamination and a poison-control consult.
- What are the key clinical points for Common Poisoning Antidotes Quick Reference?
- Supportive care and decontamination come before the antidote. Methylene blue and rasburicase are cautioned/contraindicated in G6PD deficiency. Long-acting toxins often outlast the antidote — repeat or infuse. Doses must be individualised to the toxin, amount and levels.
- What are the limits and cautions when using Common Poisoning Antidotes Quick Reference?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Common Poisoning Antidotes Quick Reference calculated in practice? Can you show a worked example?
- Inputs: Toxin Acetaminophen → Result: Antidote NAC (N-acetylcysteine)（Dose: IV 150 mg/kg (1 h) → 50 mg/kg (4 h) → 100 mg/kg (16 h), total 300 mg/kg; or oral 140 + 70 ×17, Key: Decide by the Rumack-Matthew line; see the 'Acetaminophen' tool） Inputs: Toxin Local anaesthetic systemic toxicity → Result: Antidote Lipid emulsion (20%)（Dose: 20% lipid emulsion 1.5 mL/kg bolus → 0.25 mL/kg/min infusion, Key: Continue high-quality CPR; local anaesthetic systemic toxicity (LAST)）