産科 / 麻酔 / 集中治療
羊水塞栓(AFE) — 認識と蘇生
分娩中/直後の突然の低酸素+低血圧+DIC三徴→AFEとして蘇生・大量輸血体制。
根拠:SMFM。各ノードはガイドラインの判断ロジックを要約したものであり、原文の転載ではありません。 医療従事者向けの参考情報であり、臨床判断の代替ではありません。日本の関連学会指針および施設プロトコルを優先してください。
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ステップ 1 · Sudden cardiopulmonary collapse
Sudden cardiopulmonary collapse during labor/immediately postpartum (triad of hypoxia + hypotension + coagulopathy)?
💡 Amniotic fluid embolism = a clinical diagnosis (no confirmatory test), triad: sudden hypoxia, hypotension, coagulopathy/DIC, occurring during labor or immediately postpartum (± seizure, cardiac arrest). A diagnosis of exclusion; finding fetal squamous cells in maternal blood is not diagnostic.
パス全体像
- 【判断】Sudden cardiopulmonary collapseSudden cardiopulmonary collapse during labor/immediately postpartum (triad of hypoxia + hypotension + coagulopathy)?(Amniotic fluid embolism = a clinical diagnosis (no confirmatory test), triad: sudden hypoxia, hypotension, coagulopathy/DIC, occurring during labor or immediately postpartum (± seizure, cardiac arrest). A diagnosis of exclusion; finding fetal squamous cells in maternal blood is not diagnostic.)
- Meets it (sudden collapse) → High-quality supportive resuscitation
- Does not meet it → Does not meet it
- 【終点】Does not meet it突然の虚脱の他原因(肺塞栓、出血性ショック、心原性、麻酔合併症)を評価しつつAFEとして蘇生。
- 【終点】High-quality supportive resuscitation1) Cardiac arrest → 直ちに BLS/ACLS + left uterine displacement;の場合undelivered・蘇生 is failing, perform a perimortem cesarean 4–5 minへaid 蘇生・save the fetus. 2) Airway/ventilation (挿管, 100% oxygen), circulatory support (cautious 輸液, vasopressors/inotropes, manage right heart failure・pulmonary hypertension). 3) Aggressively correct DIC: early coagulation testing, activate the massive transfusion protocol (RBC/plasma/platelets/cryoprecipitate/fibrinogen) + tranexamic acid. 4) Multidisciplinary (obstetrics, anesthesia, critical care, hematology), ICU, ECMOの場合needed.
よくある質問
- 羊水塞栓(AFE) — 認識と蘇生はどの臨床課題を扱う診療パスですか?
- 分娩中/直後の突然の低酸素+低血圧+DIC三徴→AFEとして蘇生・大量輸血体制。
- 羊水塞栓(AFE) — 認識と蘇生の主要な意思決定ステップは何ですか?
- Sudden cardiopulmonary collapse
- 羊水塞栓(AFE) — 認識と蘇生はどのような対応方針を示しますか?
- Does not meet it:突然の虚脱の他原因(肺塞栓、出血性ショック、心原性、麻酔合併症)を評価しつつAFEとして蘇生。;High-quality supportive resuscitation:1) Cardiac arrest → 直ちに BLS/ACLS + left uterine displacement;の場合undelivered・蘇生 is failing, perform a perimortem cesarean 4–5 minへaid 蘇生・save the fetus. 2) Airway/ventilation (挿管, 100% oxygen), circulatory support (cautious 輸液, vasopressors/inotropes, manage right heart failure・pulmonary hypertension). 3) Aggressively correct DIC: early coagulation testing, activate the massive transfusion protocol (RBC/plasma/platelets/cryoprecipitate/fibrinogen) + tranexamic acid. 4) Multidisciplinary (obstetrics, anesthesia, critical care, hematology), ICU, ECMOの場合needed.
- 羊水塞栓(AFE) — 認識と蘇生のうち直ちに対応が必要な状況はどれですか?
- High-quality supportive resuscitation:1) Cardiac arrest → 直ちに BLS/ACLS + left uterine displacement;の場合undelivered・蘇生 is failing, perform a perimortem cesarean 4–5 minへaid 蘇生・save the fetus. 2) Airway/ventilation (挿管, 100% oxygen), circulatory support (cautious 輸液, vasopressors/inotropes, manage right heart failure・pulmonary hypertension). 3) Aggressively correct DIC: early coagulation testing, activate the massive transfusion protocol (RBC/plasma/platelets/cryoprecipitate/fibrinogen) + tranexamic acid. 4) Multidisciplinary (obstetrics, anesthesia, critical care, hematology), ICU, ECMOの場合neede…
- 羊水塞栓(AFE) — 認識と蘇生はどのガイドラインに基づいていますか?
- SMFM Clinical Guideline No. 9: Amniotic fluid embolism diagnosis and management. Am J Obstet Gynecol 2016 · 準拠:SMFM
出典
- SMFM Clinical Guideline No. 9: Amniotic fluid embolism diagnosis and management. Am J Obstet Gynecol 2016