症例 challenge · Emergency / Toxicology / Critical care · teaching

Paraquat Poisoning — Management Pathway · case challenge

Given a case, work through the care pathway step by step; the tool checks each choice and scores you. Decisions and basis are taken from this site's reviewed care pathways.

← View the full flowchartBased on Poisoning reviews / blood-purification consensus

Case #1Emergency / Toxicology / Critical care

📋 Case data

Is oxygen needed (the key paradox)SpO2 <85% (severe hypoxemia)

Data is taken from this pathway's reviewed node text. Work through the pathway step by step.

Step 1 / 1 · Is oxygen needed (the key paradox)

What is the oxygenation status?

💡 Paraquat is a highly toxic herbicide (common in Asia, very high mortality, no specific antidote) that causes lung (pneumonitis → fibrosis), kidney and liver injury via redox cycling. Its toxicity is worsened by high-concentration oxygen (promotes oxygen free radicals/lipid peroxidation) — this is the most common mistake. Staff use PPE (gloves, gown), remove contaminated clothing.

For teaching. Decisions and their basis are taken from this site's reviewed care pathways; for licensed clinicians/trainees, this does not replace clinical judgment or local protocols.