症例 challenge · Hematology / Critical care / Emergency · teaching

Disseminated Intravascular Coagulation (DIC) — Pathway · case challenge

Given a case, work through the care pathway step by step; the tool checks each choice and scores you. Decisions and basis are taken from this site's reviewed care pathways.

← View the full flowchartBased on ISTH 2001

Case #1Hematology / Critical care / Emergency

📋 Case data

ISTH overt DIC score<5 (non-overt)

Data is taken from this pathway's reviewed node text. Work through the pathway step by step.

Step 1 / 1 · ISTH overt DIC score

ISTH overt DIC score (requires a known predisposing illness)?

💡 Requires a known predisposing illness (sepsis, trauma, malignancy, obstetric complications, heat stroke, severe immune reaction, APL). ISTH score: platelets (≥100k=0/50–100k=1/<50k=2) + fibrin marker D-dimer (no rise=0/moderate=2/strong=3) + PT prolongation (<3 s=0/3–6 s=1/>6 s=2) + fibrinogen (≥1 g/L=0/<1=1). ≥5 = overt DIC, reassess q12–24h. Progressively falling platelets is often earliest; a normal D-dimer essentially excludes it.

For teaching. Decisions and their basis are taken from this site's reviewed care pathways; for licensed clinicians/trainees, this does not replace clinical judgment or local protocols.