症例 challenge · Infectious disease / Gastroenterology / Critical care · teaching

Clostridioides difficile Colitis (CDI) — Pathway · case challenge

Given a case, work through the care pathway step by step; the tool checks each choice and scores you. Decisions and basis are taken from this site's reviewed care pathways.

← View the full flowchartBased on ACG 2021 / IDSA

Case #1Infectious disease / Gastroenterology / Critical care

📋 Case data

Severity gradeNon-severe–severe

Data is taken from this pathway's reviewed node text. Work through the pathway step by step.

Step 1 / 1 · Severity grade

Severity? (WBC/creatinine / fulminant signs)

💡 Antibiotic-associated, toxin-producing C. difficile infection (CDI); triggers: antibiotics, advanced age, PPIs, hospitalization. Diarrhea (≥3 loose stools/24 h) + cramping pain/low-grade fever/raised WBC; spectrum: asymptomatic carriage → pseudomembranous colitis → fulminant (toxic megacolon/ileus/perforation/shock). Diagnosis: stool NAAT + toxin EIA in patients with significant diarrhea (do not test asymptomatic/formed stool). Severity: non-severe (WBC <15×10⁹ and creatinine <1.5 mg/dL) / severe (WBC ≥15 or creatinine ≥1.5) / fulminant (hypotension/shock/ileus/megacolon).

For teaching. Decisions and their basis are taken from this site's reviewed care pathways; for licensed clinicians/trainees, this does not replace clinical judgment or local protocols.