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🫘 Urine Anion Gap Calculator

Calculate the urine anion gap to evaluate normal-anion-gap metabolic acidosis.

Clinical takeaway

A surrogate for urinary ammonium.

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When to use

Distinguish renal tubular acidosis from extrarenal bicarbonate loss.

How it works

UAG = UNa + UK − UCl. Negative → appropriate NH₄⁺ excretion (GI loss); positive → impaired excretion (distal RTA).

Key points

  • A surrogate for urinary ammonium.
  • Unreliable with ketoacids or other unmeasured urinary anions.
  • Interpret with serum acid–base and potassium.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Urine sodium40 mmol/L
Urine potassium30 mmol/L
Urine chloride60 mmol/L

Urine anion gap10mmol/L

  • InterpretationPositive — impaired renal NH₄⁺ excretion (e.g. distal RTA).
  • FormulaUAG = UNa + UK − UCl

Frequently asked questions

What is Urine Anion Gap Calculator?
Calculate the urine anion gap to evaluate normal-anion-gap metabolic acidosis.
How is Urine Anion Gap Calculator calculated? What is the core formula?
UAG = UNa + UK − UCl. Negative → appropriate NH₄⁺ excretion (GI loss); positive → impaired excretion (distal RTA).
When is Urine Anion Gap Calculator used?
Distinguish renal tubular acidosis from extrarenal bicarbonate loss.
What are the key clinical points for Urine Anion Gap Calculator?
A surrogate for urinary ammonium. Unreliable with ketoacids or other unmeasured urinary anions. Interpret with serum acid–base and potassium.
What are the limits and cautions when using Urine Anion Gap Calculator?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Urine Anion Gap Calculator calculated in practice? Can you show a worked example?
Inputs: Urine sodium 40 mmol/L, Urine potassium 30 mmol/L, Urine chloride 60 mmol/L → Result: Urine anion gap 10 mmol/L(Interpretation: Positive — impaired renal NH₄⁺ excretion (e.g. distal RTA)., Formula: UAG = UNa + UK − UCl)

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