🫘 eGFR Calculator (CKD-EPI 2021)
Estimate GFR with the race-free CKD-EPI 2021 creatinine equation for CKD staging.
Clinical takeaway
Race-free 2021 equation, reported per 1.73 m².
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When to use
Assess and stage chronic kidney disease (with albuminuria).
How it works
CKD-EPI 2021: 142 × min(SCr/κ,1)^α × max(SCr/κ,1)^−1.200 × 0.9938^age × (1.012 if female); κ=0.7/0.9, α=−0.241/−0.302.
Key points
- Race-free 2021 equation, reported per 1.73 m².
- Confirm eGFR < 60 over ≥ 3 months for CKD.
- Combine with albuminuria for KDIGO category.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Serum creatinine | 1.0 mg/dL |
|---|---|
| Age | 60 years |
| Sex | Male |
→eGFR86mL/min/1.73m²
- CKD GFR category：G2 (60–89)
- Equation：CKD-EPI 2021 (creatinine, race-free)
| Serum creatinine | 1.0 mg/dL |
|---|---|
| Age | 60 years |
| Sex | Female |
→eGFR64mL/min/1.73m²
- CKD GFR category：G2 (60–89)
- Equation：CKD-EPI 2021 (creatinine, race-free)
Frequently asked questions
- What is eGFR Calculator (CKD-EPI 2021)?
- Estimate GFR with the race-free CKD-EPI 2021 creatinine equation for CKD staging.
- How is eGFR Calculator (CKD-EPI 2021) calculated? What is the core formula?
- CKD-EPI 2021: 142 × min(SCr/κ,1)^α × max(SCr/κ,1)^−1.200 × 0.9938^age × (1.012 if female); κ=0.7/0.9, α=−0.241/−0.302.
- When is eGFR Calculator (CKD-EPI 2021) used?
- Assess and stage chronic kidney disease (with albuminuria).
- What are the key clinical points for eGFR Calculator (CKD-EPI 2021)?
- Race-free 2021 equation, reported per 1.73 m². Confirm eGFR < 60 over ≥ 3 months for CKD. Combine with albuminuria for KDIGO category.
- What are the limits and cautions when using eGFR Calculator (CKD-EPI 2021)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is eGFR Calculator (CKD-EPI 2021) calculated in practice? Can you show a worked example?
- Inputs: Serum creatinine 1.0 mg/dL, Age 60 years, Sex Male → Result: eGFR 86 mL/min/1.73m²（CKD GFR category: G2 (60–89), Equation: CKD-EPI 2021 (creatinine, race-free)） Inputs: Serum creatinine 1.0 mg/dL, Age 60 years, Sex Female → Result: eGFR 64 mL/min/1.73m²（CKD GFR category: G2 (60–89), Equation: CKD-EPI 2021 (creatinine, race-free)）