🫁 Pulmonary Tuberculosis Chemotherapy Regimen
This tool gives the standardized pulmonary tuberculosis chemotherapy regimen by new, retreatment, or drug-resistant status, with principles and monitoring.
Pulmonary Tuberculosis Chemotherapy Regimen
Treatment category
When to use
Use to select the regimen — 2HRZE/4HR for new susceptible TB, susceptibility-guided retreatment, and an individualized MDR regimen with referral.
How it works
New susceptible → 2HRZE/4HR (6 months) with DOT. Retreatment → susceptibility-guided (classically streptomycin-containing). RR/MDR → individualized regimen (bedaquiline, linezolid) by susceptibility, specialist-managed.
Key points
- Resistance screening before treatment is emphasized so retreatment and drug-resistant cases are never managed by blindly reusing the first-line regimen. (original synthesis · not guideline verbatim)
- DOT and full-course adherence underpin all regimens.
- Monitoring covers hepatotoxicity (H/R/Z), vision/color vision (E), and uric acid (Z).
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.