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🦠 Centor Score (Modified / McIsaac)

Estimate the likelihood of strep throat with the modified Centor (McIsaac) score.

Clinical takeaway

Confirm with rapid antigen test/culture before antibiotics in most settings.

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When to use

Decide on testing/treatment in sore throat.

How it works

1 point each: tonsillar exudate, tender anterior nodes, fever > 38°C, absence of cough; age 3–14 +1, 15–44 0, ≥ 45 −1.

Key points

  • Confirm with rapid antigen test/culture before antibiotics in most settings.
  • Low scores: no testing or antibiotics.
  • The McIsaac modification adds the age adjustment.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Tonsillar exudate/swellingNo
Tender anterior cervical nodesNo
Fever > 38°CNo
Cough absentNo (cough present)
Age3–14 (+1)

Centor (McIsaac)1

  • Strep probability~5–10%
  • GuidanceMost guidelines recommend confirming with rapid antigen test/culture before antibiotics rather than treating on score alone.
Tonsillar exudate/swellingYes (+1)
Tender anterior cervical nodesYes (+1)
Fever > 38°CYes (+1)
Cough absentYes (+1)
Age≥ 45 (−1)

Centor (McIsaac)3

  • Strep probability~28–35% — test
  • GuidanceMost guidelines recommend confirming with rapid antigen test/culture before antibiotics rather than treating on score alone.

Frequently asked questions

What is Centor Score (Modified / McIsaac)?
Estimate the likelihood of strep throat with the modified Centor (McIsaac) score.
How is Centor Score (Modified / McIsaac) calculated? What is the core formula?
1 point each: tonsillar exudate, tender anterior nodes, fever > 38°C, absence of cough; age 3–14 +1, 15–44 0, ≥ 45 −1.
When is Centor Score (Modified / McIsaac) used?
Decide on testing/treatment in sore throat.
What are the key clinical points for Centor Score (Modified / McIsaac)?
Confirm with rapid antigen test/culture before antibiotics in most settings. Low scores: no testing or antibiotics. The McIsaac modification adds the age adjustment.
What are the limits and cautions when using Centor Score (Modified / McIsaac)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Centor Score (Modified / McIsaac) calculated in practice? Can you show a worked example?
Inputs: Tonsillar exudate/swelling No, Tender anterior cervical nodes No, Fever > 38°C No, Cough absent No (cough present), Age 3–14 (+1) → Result: Centor (McIsaac) 1(Strep probability: ~5–10%, Guidance: Most guidelines recommend confirming with rapid antigen test/culture before antibiotics rather than treating on score alone.) Inputs: Tonsillar exudate/swelling Yes (+1), Tender anterior cervical nodes Yes (+1), Fever > 38°C Yes (+1), Cough absent Yes (+1), Age ≥ 45 (−1) → Result: Centor (McIsaac) 3(Strep probability: ~28–35% — test, Guidance: Most guidelines recommend confirming with rapid antigen test/culture before antibiotics rather than treating on score alone.)

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