🚨 Sepsis Bundle (Hour-1)
Turn lactate and shock status into the Surviving Sepsis Campaign Hour-1 bundle: fixed items, fluid target and vasopressor goal. Instant, browser-side.
Sepsis Bundle (Hour-1)
Blood lactate (mmol/L)
Hypotension/shock (MAP < 65 or needs vasopressor)
When to use
Prompt the time-critical Hour-1 bundle for sepsis and septic shock at the bedside.
How it works
Three fixed items always apply (measure lactate, blood cultures before antibiotics, early broad-spectrum antibiotics). Hypotension or lactate ≥ 4 → ≥ 30 mL/kg balanced crystalloid in the first 3 h; persistent hypotension → norepinephrine to MAP ≥ 65; recheck lactate at 2–4 h if > 2.
Key points
- Antibiotics within 1 h for septic shock or high suspicion; aim within 3 h for possible sepsis without shock.
- Norepinephrine is first-line and may be started peripherally to avoid delay while central access is obtained.
- Use balanced crystalloid by actual body weight (adjusted weight if BMI > 30); reassess volume responsiveness dynamically rather than repeating fixed boluses.
- Lactate clearance guides ongoing resuscitation; control the source and de-escalate by susceptibility.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.