🧬 Prognostic Nutritional Index (Onodera PNI)
Assess nutritional/immune status with the Onodera Prognostic Nutritional Index.
Clinical takeaway
Lower PNI links to more complications and worse prognosis.
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When to use
Predict surgical and oncologic risk from albumin and lymphocytes.
How it works
PNI = 10 × albumin (g/dL) + 0.005 × lymphocyte count (/µL). Values below ~45 indicate higher risk.
Key points
- Lower PNI links to more complications and worse prognosis.
- Cut-offs vary by tumour and population.
- Easy to calculate from routine labs.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Albumin | 4.0 g/dL |
|---|---|
| Total lymphocyte count | 1500 cells/µL |
→PNI47.5
- Interpretation：45–50 — mild risk
- Formula：10 × albumin (g/dL) + 0.005 × lymphocytes (/µL)
Frequently asked questions
- What is Prognostic Nutritional Index (Onodera PNI)?
- Assess nutritional/immune status with the Onodera Prognostic Nutritional Index.
- How is Prognostic Nutritional Index (Onodera PNI) calculated? What is the core formula?
- PNI = 10 × albumin (g/dL) + 0.005 × lymphocyte count (/µL). Values below ~45 indicate higher risk.
- When is Prognostic Nutritional Index (Onodera PNI) used?
- Predict surgical and oncologic risk from albumin and lymphocytes.
- What are the key clinical points for Prognostic Nutritional Index (Onodera PNI)?
- Lower PNI links to more complications and worse prognosis. Cut-offs vary by tumour and population. Easy to calculate from routine labs.
- What are the limits and cautions when using Prognostic Nutritional Index (Onodera PNI)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Prognostic Nutritional Index (Onodera PNI) calculated in practice? Can you show a worked example?
- Inputs: Albumin 4.0 g/dL, Total lymphocyte count 1500 cells/µL → Result: PNI 47.5（Interpretation: 45–50 — mild risk, Formula: 10 × albumin (g/dL) + 0.005 × lymphocytes (/µL)）