🎗️ Endometrial Cancer Mayo Lymphadenectomy Indication
Use the Mayo criteria (histology, grade, myometrial invasion, tumour size) to judge whether an endometrioid adenocarcinoma can safely be spared lymphadenectomy. Instant, browser-side.
Endometrial Cancer Mayo Lymphadenectomy Indication
Histology
Grade
Myometrial invasion depth
Maximum primary tumour diameter
When to use
Identify the low-risk endometrioid endometrial cancer group that can omit systematic lymphadenectomy.
How it works
Low-risk = endometrioid, G1–2, myometrial invasion ≤ 50%, diameter ≤ 2 cm (or no myometrial invasion at any size/grade). Any of G3 / > 50% invasion / > 2 cm / non-endometrioid = at-risk.
Key points
- The low-risk group has roughly 1–5% nodal metastasis and ~ 99% 5-year survival, and can omit systematic dissection without a survival cost.
- The at-risk group has roughly 6.4% nodal metastasis and warrants pelvic ± para-aortic dissection or sentinel-node biopsy.
- Non-endometrioid histology (serous/clear-cell/carcinosarcoma) is high-risk regardless and needs full staging.
- Contemporary practice increasingly replaces systematic lymphadenectomy with sentinel-node mapping.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.