🦠 MASCC Score (Febrile Neutropenia Risk)
Identify low-risk febrile neutropenia with the MASCC score.
Clinical takeaway
≥ 21 may permit outpatient oral therapy in selected patients.
Loading calculator…
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
When to use
Decide on outpatient versus inpatient management.
How it works
Weighted items (burden of illness, no hypotension, no COPD, tumour type, hydration, outpatient status, age) up to 26. ≥ 21 = low risk.
Key points
- ≥ 21 may permit outpatient oral therapy in selected patients.
- Apply alongside social and clinical criteria.
- Never override clinical concern.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Burden of illness | None/mild (5) |
|---|---|
| No hypotension (SBP > 90) | No |
| No COPD | No |
| Solid tumour or no prior fungal infection | No |
| No dehydration needing IV fluids | No |
| Outpatient at fever onset | No |
| Age < 60 | No |
→MASCC5/26
- Risk：< 21 — high risk; admit for IV antibiotics.
| Burden of illness | Severe (0) |
|---|---|
| No hypotension (SBP > 90) | Yes (+5) |
| No COPD | Yes (+4) |
| Solid tumour or no prior fungal infection | Yes (+4) |
| No dehydration needing IV fluids | Yes (+3) |
| Outpatient at fever onset | Yes (+3) |
| Age < 60 | Yes (+2) |
→MASCC21/26
- Risk：≥ 21 — low risk; outpatient oral therapy may be appropriate in selected patients.
Frequently asked questions
- What is MASCC Score (Febrile Neutropenia Risk)?
- Identify low-risk febrile neutropenia with the MASCC score.
- How is MASCC Score (Febrile Neutropenia Risk) calculated? What is the core formula?
- Weighted items (burden of illness, no hypotension, no COPD, tumour type, hydration, outpatient status, age) up to 26. ≥ 21 = low risk.
- When is MASCC Score (Febrile Neutropenia Risk) used?
- Decide on outpatient versus inpatient management.
- What are the key clinical points for MASCC Score (Febrile Neutropenia Risk)?
- ≥ 21 may permit outpatient oral therapy in selected patients. Apply alongside social and clinical criteria. Never override clinical concern.
- What are the limits and cautions when using MASCC Score (Febrile Neutropenia Risk)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is MASCC Score (Febrile Neutropenia Risk) calculated in practice? Can you show a worked example?
- Inputs: Burden of illness None/mild (5), No hypotension (SBP > 90) No, No COPD No, Solid tumour or no prior fungal infection No, No dehydration needing IV fluids No, Outpatient at fever onset No, Age < 60 No → Result: MASCC 5 /26（Risk: < 21 — high risk; admit for IV antibiotics.） Inputs: Burden of illness Severe (0), No hypotension (SBP > 90) Yes (+5), No COPD Yes (+4), Solid tumour or no prior fungal infection Yes (+4), No dehydration needing IV fluids Yes (+3), Outpatient at fever onset Yes (+3), Age < 60 Yes (+2) → Result: MASCC 21 /26（Risk: ≥ 21 — low risk; outpatient oral therapy may be appropriate in selected patients.）