🫀 Liver LI-RADS (CT/MRI HCC) Category
Compute the liver LI-RADS category (LR-3/4/5) from at-risk status, size and major features, with management. Instant, browser-side.
Clinical takeaway
LI-RADS applies only to patients at high risk for HCC (cirrhosis, chronic HBV, prior HCC).
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When to use
Categorise an observation on diagnostic CT/MRI in patients at high risk for HCC.
How it works
Major features — non-rim APHE, size, non-peripheral washout, enhancing capsule, threshold growth (≥ 50%/≤ 6 mo) — combine to LR-3/4/5. 10–19 mm + APHE + washout or threshold growth = LR-5.
Key points
- LI-RADS applies only to patients at high risk for HCC (cirrhosis, chronic HBV, prior HCC).
- LR-5 allows non-invasive HCC diagnosis without biopsy.
- LR-M (non-HCC malignancy) and LR-TIV (venous invasion) are adjudicated separately.
- Capsule alone vs washout/threshold-growth changes the category in the 10–19 mm + APHE band.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| At high risk for HCC (cirrhosis / chronic HBV / prior HCC) | Yes |
|---|---|
| Lesion size | 15 mm |
| Non-rim arterial-phase hyper-enhancement (APHE) | Yes |
| Non-peripheral washout | Yes |
| Enhancing capsule | Yes |
| Threshold growth (≥ 50% / ≤ 6 months) | Yes |
→CategoryLR-5
- Category：LR-5 (definite HCC)
- Read：Non-rim APHE present, size 15 mm, 3 additional major feature(s) (non-peripheral washout ✓, enhancing capsule ✓, threshold growth ✓)
- Management：Definite HCC: non-invasive imaging diagnosis without biopsy; multidisciplinary HCC staging and treatment (resection/ablation/transplant/transarterial/systemic)
| At high risk for HCC (cirrhosis / chronic HBV / prior HCC) | No |
|---|---|
| Lesion size | 15 mm |
| Non-rim arterial-phase hyper-enhancement (APHE) | No |
| Non-peripheral washout | No |
| Enhancing capsule | No |
| Threshold growth (≥ 50% / ≤ 6 months) | No |
→ApplicabilityLI-RADS not applicable
- Eligible population：Diagnostic CT/MRI LI-RADS applies only to patients at high risk for HCC: cirrhosis, chronic HBV, or current/prior HCC; not for age < 18, no risk factors, or cirrhosis from congenital hepatic fibrosis or vascular causes
- Advice：Evaluate liver lesions in non-at-risk patients along a general liver-lesion diagnostic pathway
- Basis：ACR LI-RADS v2018 CT/MRI diagnosis
Frequently asked questions
- What is Liver LI-RADS (CT/MRI HCC) Category?
- Compute the liver LI-RADS category (LR-3/4/5) from at-risk status, size and major features, with management. Instant, browser-side.
- How is Liver LI-RADS (CT/MRI HCC) Category calculated? What is the core formula?
- Major features — non-rim APHE, size, non-peripheral washout, enhancing capsule, threshold growth (≥ 50%/≤ 6 mo) — combine to LR-3/4/5. 10–19 mm + APHE + washout or threshold growth = LR-5.
- When is Liver LI-RADS (CT/MRI HCC) Category used?
- Categorise an observation on diagnostic CT/MRI in patients at high risk for HCC.
- What are the key clinical points for Liver LI-RADS (CT/MRI HCC) Category?
- LI-RADS applies only to patients at high risk for HCC (cirrhosis, chronic HBV, prior HCC). LR-5 allows non-invasive HCC diagnosis without biopsy. LR-M (non-HCC malignancy) and LR-TIV (venous invasion) are adjudicated separately. Capsule alone vs washout/threshold-growth changes the category in the 10–19 mm + APHE band.
- What are the limits and cautions when using Liver LI-RADS (CT/MRI HCC) Category?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Liver LI-RADS (CT/MRI HCC) Category calculated in practice? Can you show a worked example?
- Inputs: At high risk for HCC (cirrhosis / chronic HBV / prior HCC) Yes, Lesion size 15 mm, Non-rim arterial-phase hyper-enhancement (APHE) Yes, Non-peripheral washout Yes, Enhancing capsule Yes, Threshold growth (≥ 50% / ≤ 6 months) Yes → Result: Category LR-5（Category: LR-5 (definite HCC), Read: Non-rim APHE present, size 15 mm, 3 additional major feature(s) (non-peripheral washout ✓, enhancing capsule ✓, threshold growth ✓), Management: Definite HCC: non-invasive imaging diagnosis without biopsy; multidisciplinary HCC staging and treatment (resection/ablation/transplant/transarterial/systemic)） Inputs: At high risk for HCC (cirrhosis / chronic HBV / prior HCC) No, Lesion size 15 mm, Non-rim arterial-phase hyper-enhancement (APHE) No, Non-peripheral washout No, Enhancing capsule No, Threshold growth (≥ 50% / ≤ 6 months) No → Result: Applicability LI-RADS not applicable（Eligible population: Diagnostic CT/MRI LI-RADS applies only to patients at high risk for HCC: cirrhosis, chronic HBV, or current/prior HCC; not for age < 18, no risk factors, or cirrhosis from congenital hepatic fibrosis or vascular causes, Advice: Evaluate liver lesions in non-at-risk patients along a general liver-lesion diagnostic pathway, Basis: ACR LI-RADS v2018 CT/MRI diagnosis）