🫘 KDIGO Acute Kidney Injury Staging
KDIGO staging classifies acute kidney injury severity from serum creatinine change, urine output, and dialysis status.
AKI is diagnosed by a creatinine rise ≥26.5 μmol/L within 48h or ≥1.5× baseline within 7 days (original synthesis · not guideline verbatim).
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When to use
Enter current and baseline creatinine and the worst urine-output criterion; the tool returns the AKI stage (1–3) taking the most severe component.
How it works
Stage = max of creatinine stage and urine-output stage; dialysis = stage 3. Cr stage 3 if ≥353.6 μmol/L or ≥3× baseline; stage 2 if ≥2×; stage 1 if ≥1.5× or rise ≥26.5 μmol/L.
Key points
- AKI is diagnosed by a creatinine rise ≥26.5 μmol/L within 48h or ≥1.5× baseline within 7 days (original synthesis · not guideline verbatim).
- Establishing an accurate baseline and excluding volume/sampling confounders is essential before staging.
- Urine-output criteria can stage AKI even when creatinine has not yet risen, so both must be tracked.
References
- KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl. 2012.
- Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Current serum creatinine | 180 μmol/L |
|---|---|
| Baseline serum creatinine | 80 μmol/L |
| Urine-output criterion (take the most severe) | No significant oliguria |
| Renal replacement therapy (dialysis) started | Yes |
→AKI stageStage 3
- Creatinine ratio：2.25 (scores stage 2)
- Urine-output score：stage 0
Frequently asked questions
- What is KDIGO Acute Kidney Injury Staging?
- KDIGO staging classifies acute kidney injury severity from serum creatinine change, urine output, and dialysis status.
- How is KDIGO Acute Kidney Injury Staging calculated? What is the core formula?
- Stage = max of creatinine stage and urine-output stage; dialysis = stage 3. Cr stage 3 if ≥353.6 μmol/L or ≥3× baseline; stage 2 if ≥2×; stage 1 if ≥1.5× or rise ≥26.5 μmol/L.
- When is KDIGO Acute Kidney Injury Staging used?
- Enter current and baseline creatinine and the worst urine-output criterion; the tool returns the AKI stage (1–3) taking the most severe component.
- What are the key clinical points for KDIGO Acute Kidney Injury Staging?
- AKI is diagnosed by a creatinine rise ≥26.5 μmol/L within 48h or ≥1.5× baseline within 7 days (original synthesis · not guideline verbatim). Establishing an accurate baseline and excluding volume/sampling confounders is essential before staging. Urine-output criteria can stage AKI even when creatinine has not yet risen, so both must be tracked.
- What are the limits and cautions when using KDIGO Acute Kidney Injury Staging?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is KDIGO Acute Kidney Injury Staging calculated in practice? Can you show a worked example?
- Inputs: Current serum creatinine 180 μmol/L, Baseline serum creatinine 80 μmol/L, Urine-output criterion (take the most severe) No significant oliguria, Renal replacement therapy (dialysis) started Yes → Result: AKI stage Stage 3（Creatinine ratio: 2.25 (scores stage 2), Urine-output score: stage 0）