🫀 Glasgow Alcoholic Hepatitis Score (GAHS)
Estimate prognosis in alcoholic hepatitis with the Glasgow Alcoholic Hepatitis Score (GAHS).
Clinical takeaway
In severe disease (Maddrey DF ≥ 32), GAHS ≥ 9 predicts steroid benefit.
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When to use
Identify patients likely to benefit from corticosteroids.
How it works
Points for age, WBC, urea, INR and bilirubin (total 5–12). GAHS ≥ 9 indicates poor prognosis.
Key points
- In severe disease (Maddrey DF ≥ 32), GAHS ≥ 9 predicts steroid benefit.
- Combines clinical and laboratory variables.
- Reassess steroid response with the Lille score.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | < 50 (1) |
|---|---|
| WBC (×10⁹/L) | < 15 (1) |
| Urea (mmol/L) | < 5 (1) |
| INR | < 1.5 (1) |
| Bilirubin (µmol/L) | < 125 (1) |
→GAHS5/12
- Interpretation：< 9 — better prognosis; steroid benefit less clear.
| Age | ≥ 50 (2) |
|---|---|
| WBC (×10⁹/L) | ≥ 15 (2) |
| Urea (mmol/L) | ≥ 5 (2) |
| INR | > 2.0 (3) |
| Bilirubin (µmol/L) | > 250 (3) |
→GAHS12/12
- Interpretation：≥ 9 — poor prognosis; corticosteroids likely to improve survival (in severe disease, DF ≥ 32).
Frequently asked questions
- What is Glasgow Alcoholic Hepatitis Score (GAHS)?
- Estimate prognosis in alcoholic hepatitis with the Glasgow Alcoholic Hepatitis Score (GAHS).
- How is Glasgow Alcoholic Hepatitis Score (GAHS) calculated? What is the core formula?
- Points for age, WBC, urea, INR and bilirubin (total 5–12). GAHS ≥ 9 indicates poor prognosis.
- When is Glasgow Alcoholic Hepatitis Score (GAHS) used?
- Identify patients likely to benefit from corticosteroids.
- What are the key clinical points for Glasgow Alcoholic Hepatitis Score (GAHS)?
- In severe disease (Maddrey DF ≥ 32), GAHS ≥ 9 predicts steroid benefit. Combines clinical and laboratory variables. Reassess steroid response with the Lille score.
- What are the limits and cautions when using Glasgow Alcoholic Hepatitis Score (GAHS)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Glasgow Alcoholic Hepatitis Score (GAHS) calculated in practice? Can you show a worked example?
- Inputs: Age < 50 (1), WBC (×10⁹/L) < 15 (1), Urea (mmol/L) < 5 (1), INR < 1.5 (1), Bilirubin (µmol/L) < 125 (1) → Result: GAHS 5 /12（Interpretation: < 9 — better prognosis; steroid benefit less clear.） Inputs: Age ≥ 50 (2), WBC (×10⁹/L) ≥ 15 (2), Urea (mmol/L) ≥ 5 (2), INR > 2.0 (3), Bilirubin (µmol/L) > 250 (3) → Result: GAHS 12 /12（Interpretation: ≥ 9 — poor prognosis; corticosteroids likely to improve survival (in severe disease, DF ≥ 32).）