Adenomyosis · Medical vs Uterus-Sparing vs Hysterectomy
Medical (LNG-IUS/GnRH/progestin) first; uterus-sparing = lesion excision/UAE/HIFU; completed childbearing/definitive → hysterectomy.
Medical/conservative: Medical: LNG-IUS (Mirena) preferred, GnRH agonist (preoperative/short-term), oral progestin/COC, tranexamic acid for menorrhagia; failure/i…
Step-by-step decision
Choose step by step as prompted; reaching an endpoint gives the management recommendation. You can go back a step or restart anytime.
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Full pathway
- [Decision] Symptoms + fertility wishSymptom severity? Preserve uterus/fertility?
- Symptomatic, try medical/conservative first → Medical/conservative
- Symptomatic, wants to preserve uterus/fertility → Preserve uterus → lesion excision/UAE/HIFU
- Symptomatic, completed childbearing/wants definitive cure → Completed childbearing → hysterectomy
- [End] Medical/conservativeMedical: LNG-IUS (Mirena) preferred, GnRH agonist (preoperative/short-term), oral progestin/COC, tranexamic acid for menorrhagia; failure/intolerance → surgery.
- [End] Preserve uterus → lesion excision/UAE/HIFUUterus-sparing → adenomyomectomy (diffuse disease resects incompletely and recurs easily), uterine artery embolization (UAE), HIFU; weigh recurrence against fertility and uterine rupture risk in pregnancy.
- [End] Completed childbearing → hysterectomyCompleted childbearing/wants definitive cure → hysterectomy (definitive cure); abdominal/laparoscopic/vaginal by uterine size and surgeon.
Source guidelines & references
- Adenomyosis management (ACOG; ESHRE endometriosis/adenomyosis)
This pathway is our own synthesis of the decision logic in the guidelines above (not the guideline verbatim); thresholds and workflows change as guidelines update — in practice follow the latest guideline, your institution's protocol and the individual patient.
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