🫁 Simplified PESI (PE 30-day Mortality)
Risk-stratify acute pulmonary embolism for 30-day mortality with the simplified PESI.
Clinical takeaway
A score of 0 (~1% mortality) supports outpatient management.
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When to use
Identify low-risk PE potentially suitable for outpatient treatment.
How it works
1 point each: age > 80, cancer, chronic cardiopulmonary disease, HR ≥ 110, SBP < 100, SaO₂ < 90%. 0 = low risk; ≥ 1 = high risk.
Key points
- A score of 0 (~1% mortality) supports outpatient management.
- Any positive item makes the patient high-risk.
- Combine with Hestia criteria and clinical judgement.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age > 80 | No |
|---|---|
| History of cancer | No |
| Chronic cardiopulmonary disease | No |
| Heart rate ≥ 110 | No |
| Systolic BP < 100 | No |
| SaO₂ < 90% | No |
→sPESI0
- Interpretation：Low risk (~1% 30-day mortality) — consider outpatient treatment.
| Age > 80 | Yes (+1) |
|---|---|
| History of cancer | Yes (+1) |
| Chronic cardiopulmonary disease | Yes (+1) |
| Heart rate ≥ 110 | Yes (+1) |
| Systolic BP < 100 | Yes (+1) |
| SaO₂ < 90% | Yes (+1) |
→sPESI6
- Interpretation：High risk (~10%) — not suitable for outpatient management.
Frequently asked questions
- What is Simplified PESI (PE 30-day Mortality)?
- Risk-stratify acute pulmonary embolism for 30-day mortality with the simplified PESI.
- How is Simplified PESI (PE 30-day Mortality) calculated? What is the core formula?
- 1 point each: age > 80, cancer, chronic cardiopulmonary disease, HR ≥ 110, SBP < 100, SaO₂ < 90%. 0 = low risk; ≥ 1 = high risk.
- When is Simplified PESI (PE 30-day Mortality) used?
- Identify low-risk PE potentially suitable for outpatient treatment.
- What are the key clinical points for Simplified PESI (PE 30-day Mortality)?
- A score of 0 (~1% mortality) supports outpatient management. Any positive item makes the patient high-risk. Combine with Hestia criteria and clinical judgement.
- What are the limits and cautions when using Simplified PESI (PE 30-day Mortality)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Simplified PESI (PE 30-day Mortality) calculated in practice? Can you show a worked example?
- Inputs: Age > 80 No, History of cancer No, Chronic cardiopulmonary disease No, Heart rate ≥ 110 No, Systolic BP < 100 No, SaO₂ < 90% No → Result: sPESI 0（Interpretation: Low risk (~1% 30-day mortality) — consider outpatient treatment.） Inputs: Age > 80 Yes (+1), History of cancer Yes (+1), Chronic cardiopulmonary disease Yes (+1), Heart rate ≥ 110 Yes (+1), Systolic BP < 100 Yes (+1), SaO₂ < 90% Yes (+1) → Result: sPESI 6（Interpretation: High risk (~10%) — not suitable for outpatient management.）