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🫁 PERC Rule (PE Rule-out Criteria)

Apply the PERC rule to exclude pulmonary embolism without D-dimer in low-risk patients.

PERC Rule (PE Rule-out Criteria)

Age ≥ 50
Heart rate ≥ 100
SpO₂ < 95%
Haemoptysis
Oestrogen use
Prior DVT/PE
Unilateral leg swelling
Surgery/trauma ≤ 4 weeks (needing hospitalisation)

When to use

Rule out PE when clinical pre-test probability is already low.

How it works

Eight criteria (age ≥ 50, HR ≥ 100, SpO₂ < 95%, haemoptysis, oestrogen, prior DVT/PE, unilateral leg swelling, surgery/trauma ≤ 4 weeks). If all are negative, PE is excluded.

Key points

  • Only valid in low pre-test-probability patients.
  • Any positive criterion means PERC fails — proceed with workup.
  • Avoids unnecessary D-dimer testing.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

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