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🫃 Serum-Ascites Albumin Gradient (SAAG)

Determine whether ascites is due to portal hypertension with the SAAG.

Serum-Ascites Albumin Gradient (SAAG)

Serum albumin (g/dL)
Ascites albumin (g/dL)

When to use

Classify ascites in the diagnostic work-up.

How it works

SAAG = serum albumin − ascites albumin (same-day samples). ≥ 1.1 g/dL indicates portal hypertension.

Key points

  • ≥ 1.1 g/dL is ~97% accurate for portal hypertension.
  • Add ascitic total protein to separate cardiac from cirrhotic ascites.
  • < 1.1 suggests malignancy, TB or pancreatitis.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

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