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🎗️ Karnofsky Performance Status (KPS)

The Karnofsky Performance Status scores a patient's functional capacity and self-care from 0 to 100.

Clinical takeaway

KPS ≥70 generally indicates a patient able to tolerate active anticancer therapy, while <40 favors supportive/palliative goals (original synthesis · not guideline verbatim).

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When to use

Select the descriptor that best matches the patient; the tool returns the KPS value and a self-care band.

How it works

KPS is a single 0–100 ordinal scale in 10-point steps; ≥80 ok, 60–70 intermediate, 40–50 warning, <40 poor.

Key points

  • KPS ≥70 generally indicates a patient able to tolerate active anticancer therapy, while <40 favors supportive/palliative goals (original synthesis · not guideline verbatim).
  • KPS maps approximately to ECOG (KPS 90–100 ≈ ECOG 0, 70–80 ≈ ECOG 1) and the two are often used interchangeably.
  • Performance status is one of the strongest independent predictors of survival across cancers.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Performance status100: Normal, no complaints or signs

KPS100

  • Self-careLargely independent
Performance status10: Moribund

KPS10

  • Self-careFully dependent

Frequently asked questions

What is Karnofsky Performance Status (KPS)?
The Karnofsky Performance Status scores a patient's functional capacity and self-care from 0 to 100.
How is Karnofsky Performance Status (KPS) calculated? What is the core formula?
KPS is a single 0–100 ordinal scale in 10-point steps; ≥80 ok, 60–70 intermediate, 40–50 warning, <40 poor.
When is Karnofsky Performance Status (KPS) used?
Select the descriptor that best matches the patient; the tool returns the KPS value and a self-care band.
What are the key clinical points for Karnofsky Performance Status (KPS)?
KPS ≥70 generally indicates a patient able to tolerate active anticancer therapy, while <40 favors supportive/palliative goals (original synthesis · not guideline verbatim). KPS maps approximately to ECOG (KPS 90–100 ≈ ECOG 0, 70–80 ≈ ECOG 1) and the two are often used interchangeably. Performance status is one of the strongest independent predictors of survival across cancers.
What are the limits and cautions when using Karnofsky Performance Status (KPS)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Karnofsky Performance Status (KPS) calculated in practice? Can you show a worked example?
Inputs: Performance status 100: Normal, no complaints or signs → Result: KPS 100(Self-care: Largely independent) Inputs: Performance status 10: Moribund → Result: KPS 10(Self-care: Fully dependent)

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