🩸 Hemolysis Marker Interpretation
Laboratory markers of haemolysis (LDH, haptoglobin, indirect bilirubin, reticulocytes, smear), intra- vs extravascular, DAT triage and causes. Browser-side.
Hemolysis Marker Interpretation
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When to use
Confirm haemolysis, then classify by DAT (immune vs non-immune) and the intravascular/extravascular pattern to find the cause.
How it works
Haemolysis: LDH ↑ + haptoglobin ↓ + indirect bilirubin ↑ + reticulocytes ↑.
Key points
- LDH ↑ with haptoglobin ↓ is sensitive and specific for haemolysis.
- DAT separates immune (AIHA) from non-immune haemolysis.
- Schistocytes flag microangiopathic haemolysis (MAHA).
- MAHA needs urgent workup for TTP/HUS/DIC.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.