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🎗️ GTN FIGO Anatomic Stage

Assign the FIGO 2000 anatomic stage (I–IV) for gestational trophoblastic neoplasia, expressed together with the WHO/FIGO prognostic score (e.g. III:7). Instant, browser-side.

Clinical takeaway

Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment.

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When to use

Anatomic staging of GTN, used jointly with the prognostic score to guide single-agent vs combination chemotherapy.

How it works

I confined to uterus; II outside uterus but limited to genital structures (adnexa/vagina/broad ligament); III lung metastasis (± genital tract); IV other distant (brain/liver/kidney/GI). Expressed with the prognostic score as Stage:Score.

Key points

  • Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment.
  • GTN has no regional nodal staging — nodal disease is classed as M1b and is uncommon.
  • Prognostic score ≤ 6 is low-risk (single-agent MTX/actinomycin D); ≥ 7 is high-risk (combination, e.g. EMA-CO).
  • Even stage IV GTN has a relatively good prognosis compared with other solid tumours, especially lung-only disease.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Extent of diseaseConfined to uterus (I)

FIGO anatomic stageStage I

  • Anatomic stageStage I: confined to uterus
  • ExpressionAnatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool)
  • Treatment linkLow-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)
Extent of diseaseOther distant: brain/liver/kidney/GI etc. (IV)

FIGO anatomic stageStage IV

  • Anatomic stageStage IV: all other distant metastases (brain, liver, kidney, GI, etc.)
  • ExpressionAnatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool)
  • Treatment linkLow-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)

Frequently asked questions

What is GTN FIGO Anatomic Stage?
Assign the FIGO 2000 anatomic stage (I–IV) for gestational trophoblastic neoplasia, expressed together with the WHO/FIGO prognostic score (e.g. III:7). Instant, browser-side.
How is GTN FIGO Anatomic Stage calculated? What is the core formula?
I confined to uterus; II outside uterus but limited to genital structures (adnexa/vagina/broad ligament); III lung metastasis (± genital tract); IV other distant (brain/liver/kidney/GI). Expressed with the prognostic score as Stage:Score.
When is GTN FIGO Anatomic Stage used?
Anatomic staging of GTN, used jointly with the prognostic score to guide single-agent vs combination chemotherapy.
What are the key clinical points for GTN FIGO Anatomic Stage?
Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment. GTN has no regional nodal staging — nodal disease is classed as M1b and is uncommon. Prognostic score ≤ 6 is low-risk (single-agent MTX/actinomycin D); ≥ 7 is high-risk (combination, e.g. EMA-CO). Even stage IV GTN has a relatively good prognosis compared with other solid tumours, especially lung-only disease.
What are the limits and cautions when using GTN FIGO Anatomic Stage?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is GTN FIGO Anatomic Stage calculated in practice? Can you show a worked example?
Inputs: Extent of disease Confined to uterus (I) → Result: FIGO anatomic stage Stage I(Anatomic stage: Stage I: confined to uterus, Expression: Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool), Treatment link: Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)) Inputs: Extent of disease Other distant: brain/liver/kidney/GI etc. (IV) → Result: FIGO anatomic stage Stage IV(Anatomic stage: Stage IV: all other distant metastases (brain, liver, kidney, GI, etc.), Expression: Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool), Treatment link: Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX))

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