🎗️ GTN FIGO Anatomic Stage
Assign the FIGO 2000 anatomic stage (I–IV) for gestational trophoblastic neoplasia, expressed together with the WHO/FIGO prognostic score (e.g. III:7). Instant, browser-side.
Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment.
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When to use
Anatomic staging of GTN, used jointly with the prognostic score to guide single-agent vs combination chemotherapy.
How it works
I confined to uterus; II outside uterus but limited to genital structures (adnexa/vagina/broad ligament); III lung metastasis (± genital tract); IV other distant (brain/liver/kidney/GI). Expressed with the prognostic score as Stage:Score.
Key points
- Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment.
- GTN has no regional nodal staging — nodal disease is classed as M1b and is uncommon.
- Prognostic score ≤ 6 is low-risk (single-agent MTX/actinomycin D); ≥ 7 is high-risk (combination, e.g. EMA-CO).
- Even stage IV GTN has a relatively good prognosis compared with other solid tumours, especially lung-only disease.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Extent of disease | Confined to uterus (I) |
|---|
→FIGO anatomic stageStage I
- Anatomic stage:Stage I: confined to uterus
- Expression:Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool)
- Treatment link:Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)
| Extent of disease | Other distant: brain/liver/kidney/GI etc. (IV) |
|---|
→FIGO anatomic stageStage IV
- Anatomic stage:Stage IV: all other distant metastases (brain, liver, kidney, GI, etc.)
- Expression:Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool)
- Treatment link:Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)
Frequently asked questions
- What is GTN FIGO Anatomic Stage?
- Assign the FIGO 2000 anatomic stage (I–IV) for gestational trophoblastic neoplasia, expressed together with the WHO/FIGO prognostic score (e.g. III:7). Instant, browser-side.
- How is GTN FIGO Anatomic Stage calculated? What is the core formula?
- I confined to uterus; II outside uterus but limited to genital structures (adnexa/vagina/broad ligament); III lung metastasis (± genital tract); IV other distant (brain/liver/kidney/GI). Expressed with the prognostic score as Stage:Score.
- When is GTN FIGO Anatomic Stage used?
- Anatomic staging of GTN, used jointly with the prognostic score to guide single-agent vs combination chemotherapy.
- What are the key clinical points for GTN FIGO Anatomic Stage?
- Stage and prognostic score are reported together (e.g. III:7); stage alone does not determine treatment. GTN has no regional nodal staging — nodal disease is classed as M1b and is uncommon. Prognostic score ≤ 6 is low-risk (single-agent MTX/actinomycin D); ≥ 7 is high-risk (combination, e.g. EMA-CO). Even stage IV GTN has a relatively good prognosis compared with other solid tumours, especially lung-only disease.
- What are the limits and cautions when using GTN FIGO Anatomic Stage?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is GTN FIGO Anatomic Stage calculated in practice? Can you show a worked example?
- Inputs: Extent of disease Confined to uterus (I) → Result: FIGO anatomic stage Stage I(Anatomic stage: Stage I: confined to uterus, Expression: Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool), Treatment link: Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX)) Inputs: Extent of disease Other distant: brain/liver/kidney/GI etc. (IV) → Result: FIGO anatomic stage Stage IV(Anatomic stage: Stage IV: all other distant metastases (brain, liver, kidney, GI, etc.), Expression: Anatomic stage (Roman I–IV) + WHO/FIGO prognostic score (Arabic) are expressed together, e.g. 「III:7」; score ≤ 6 low-risk, ≥ 7 high-risk (see the GTN prognostic score tool), Treatment link: Low-risk (score ≤ 6) usually uses single-agent chemotherapy (MTX/actinomycin D); high-risk (≥ 7) or with high-risk features uses combination chemotherapy (EMA-CO); brain/liver metastasis is individualised (radiation/surgery/intrathecal MTX))