🧬 FLIPI (Follicular Lymphoma IPI)
Prognosticate follicular lymphoma with the FLIPI index.
Clinical takeaway
Predicts overall survival across risk groups.
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When to use
Risk-stratify newly diagnosed follicular lymphoma.
How it works
One point each for age ≥ 60, stage III/IV, Hb < 12 g/dL, > 4 nodal areas, elevated LDH. 0–1 low, 2 intermediate, ≥ 3 high.
Key points
- Predicts overall survival across risk groups.
- FLIPI-2 is an alternative using different variables.
- Informs but does not dictate treatment timing.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age ≥ 60 | No |
|---|---|
| Ann Arbor stage III–IV | No |
| Haemoglobin < 12 g/dL | No |
| > 4 nodal areas | No |
| LDH > normal | No |
→FLIPI0/5
- Risk group：Low risk
| Age ≥ 60 | Yes (+1) |
|---|---|
| Ann Arbor stage III–IV | Yes (+1) |
| Haemoglobin < 12 g/dL | Yes (+1) |
| > 4 nodal areas | Yes (+1) |
| LDH > normal | Yes (+1) |
→FLIPI5/5
- Risk group：High risk
Frequently asked questions
- What is FLIPI (Follicular Lymphoma IPI)?
- Prognosticate follicular lymphoma with the FLIPI index.
- How is FLIPI (Follicular Lymphoma IPI) calculated? What is the core formula?
- One point each for age ≥ 60, stage III/IV, Hb < 12 g/dL, > 4 nodal areas, elevated LDH. 0–1 low, 2 intermediate, ≥ 3 high.
- When is FLIPI (Follicular Lymphoma IPI) used?
- Risk-stratify newly diagnosed follicular lymphoma.
- What are the key clinical points for FLIPI (Follicular Lymphoma IPI)?
- Predicts overall survival across risk groups. FLIPI-2 is an alternative using different variables. Informs but does not dictate treatment timing.
- What are the limits and cautions when using FLIPI (Follicular Lymphoma IPI)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is FLIPI (Follicular Lymphoma IPI) calculated in practice? Can you show a worked example?
- Inputs: Age ≥ 60 No, Ann Arbor stage III–IV No, Haemoglobin < 12 g/dL No, > 4 nodal areas No, LDH > normal No → Result: FLIPI 0 /5（Risk group: Low risk） Inputs: Age ≥ 60 Yes (+1), Ann Arbor stage III–IV Yes (+1), Haemoglobin < 12 g/dL Yes (+1), > 4 nodal areas Yes (+1), LDH > normal Yes (+1) → Result: FLIPI 5 /5（Risk group: High risk）