🦴 DAS28-ESR (Rheumatoid Arthritis Activity)
Measure rheumatoid arthritis disease activity with DAS28-ESR.
Clinical takeaway
ESR and CRP versions are not interchangeable.
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When to use
Treat-to-target management of rheumatoid arthritis.
How it works
0.56·√TJC28 + 0.28·√SJC28 + 0.70·ln(ESR) + 0.014·global health. < 2.6 remission, > 5.1 high.
Key points
- ESR and CRP versions are not interchangeable.
- Track the same version over time.
- Drives escalation/de-escalation of therapy.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Tender joint count (0–28) | 5 |
|---|---|
| Swollen joint count (0–28) | 3 |
| ESR | 30 mm/h |
| Patient global health (0–100) | 40 mm |
→DAS28-ESR4.68
- Category：Moderate activity
- Thresholds：< 2.6 remission, ≤ 3.2 low, ≤ 5.1 moderate, > 5.1 high
Frequently asked questions
- What is DAS28-ESR (Rheumatoid Arthritis Activity)?
- Measure rheumatoid arthritis disease activity with DAS28-ESR.
- How is DAS28-ESR (Rheumatoid Arthritis Activity) calculated? What is the core formula?
- 0.56·√TJC28 + 0.28·√SJC28 + 0.70·ln(ESR) + 0.014·global health. < 2.6 remission, > 5.1 high.
- When is DAS28-ESR (Rheumatoid Arthritis Activity) used?
- Treat-to-target management of rheumatoid arthritis.
- What are the key clinical points for DAS28-ESR (Rheumatoid Arthritis Activity)?
- ESR and CRP versions are not interchangeable. Track the same version over time. Drives escalation/de-escalation of therapy.
- What are the limits and cautions when using DAS28-ESR (Rheumatoid Arthritis Activity)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is DAS28-ESR (Rheumatoid Arthritis Activity) calculated in practice? Can you show a worked example?
- Inputs: Tender joint count (0–28) 5, Swollen joint count (0–28) 3, ESR 30 mm/h, Patient global health (0–100) 40 mm → Result: DAS28-ESR 4.68（Category: Moderate activity, Thresholds: < 2.6 remission, ≤ 3.2 low, ≤ 5.1 moderate, > 5.1 high）