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🦴 CDAI (Clinical Disease Activity Index, RA)

Calculate the Clinical Disease Activity Index (CDAI) for rheumatoid arthritis — a lab-free, immediately available activity measure.

Clinical takeaway

Excludes acute-phase reactants, so it can be scored instantly.

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When to use

Assess RA disease activity at the bedside and support treat-to-target follow-up.

How it works

CDAI = tender joints (0–28) + swollen joints (0–28) + patient global (0–10) + physician global (0–10). ≤ 2.8 remission, ≤ 10 low, ≤ 22 moderate, > 22 high.

Key points

  • Excludes acute-phase reactants, so it can be scored instantly.
  • Complements DAS28 and SDAI.
  • Useful for treat-to-target monitoring.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Tender joint count (0–28)5 joints
Swollen joint count (0–28)3 joints
Patient global assessment (0–10)4 cm
Physician global assessment (0–10)3 cm

CDAI15.0

  • Disease activityModerate activity

Frequently asked questions

What is CDAI (Clinical Disease Activity Index, RA)?
Calculate the Clinical Disease Activity Index (CDAI) for rheumatoid arthritis — a lab-free, immediately available activity measure.
How is CDAI (Clinical Disease Activity Index, RA) calculated? What is the core formula?
CDAI = tender joints (0–28) + swollen joints (0–28) + patient global (0–10) + physician global (0–10). ≤ 2.8 remission, ≤ 10 low, ≤ 22 moderate, > 22 high.
When is CDAI (Clinical Disease Activity Index, RA) used?
Assess RA disease activity at the bedside and support treat-to-target follow-up.
What are the key clinical points for CDAI (Clinical Disease Activity Index, RA)?
Excludes acute-phase reactants, so it can be scored instantly. Complements DAS28 and SDAI. Useful for treat-to-target monitoring.
What are the limits and cautions when using CDAI (Clinical Disease Activity Index, RA)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is CDAI (Clinical Disease Activity Index, RA) calculated in practice? Can you show a worked example?
Inputs: Tender joint count (0–28) 5 joints, Swollen joint count (0–28) 3 joints, Patient global assessment (0–10) 4 cm, Physician global assessment (0–10) 3 cm → Result: CDAI 15.0(Disease activity: Moderate activity)

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