🩸 CRUSADE Bleeding Risk Score
The CRUSADE score estimates baseline in-hospital major-bleeding risk in NSTE-ACS patients.
For high-risk scores, prefer radial access and dose-adjusted antithrombotics to mitigate bleeding (original synthesis · not guideline verbatim).
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When to use
Enter hematocrit, creatinine clearance, heart rate, systolic BP, and four categorical features; the tool returns the score, risk band, and estimated bleeding rate.
How it works
Weighted points from hematocrit, CrCl, heart rate, and systolic BP plus female sex (8), heart-failure signs (7), prior vascular disease (6), and diabetes (6). Strata: ≤20 very low to >50 very high.
Key points
- For high-risk scores, prefer radial access and dose-adjusted antithrombotics to mitigate bleeding (original synthesis · not guideline verbatim).
- Creatinine clearance should be computed by Cockcroft-Gault for consistency with the derivation cohort.
- Bleeding risk must be weighed against ischemic risk rather than used to withhold indicated antithrombotic therapy outright.
References
- Subherwal S, et al. Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE score. Circulation. 2009.
- Collet JP, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Baseline hematocrit | 38 % |
|---|---|
| Creatinine clearance CrCl | 70 mL/min |
| Heart rate | 80 bpm |
| Systolic blood pressure | 130 mmHg |
| Female | Yes |
| Signs of heart failure at admission | Yes |
| Prior vascular disease | Yes |
| Diabetes mellitus | Yes |
→CRUSADE score48pts
- Bleeding risk group：High
- In-hospital major bleeding (approx.)：11.9%
| Baseline hematocrit | 38 % |
|---|---|
| Creatinine clearance CrCl | 70 mL/min |
| Heart rate | 80 bpm |
| Systolic blood pressure | 130 mmHg |
| Female | No |
| Signs of heart failure at admission | No |
| Prior vascular disease | No |
| Diabetes mellitus | No |
→CRUSADE score21pts
- Bleeding risk group：Low
- In-hospital major bleeding (approx.)：5.5%
Frequently asked questions
- What is CRUSADE Bleeding Risk Score?
- The CRUSADE score estimates baseline in-hospital major-bleeding risk in NSTE-ACS patients.
- How is CRUSADE Bleeding Risk Score calculated? What is the core formula?
- Weighted points from hematocrit, CrCl, heart rate, and systolic BP plus female sex (8), heart-failure signs (7), prior vascular disease (6), and diabetes (6). Strata: ≤20 very low to >50 very high.
- When is CRUSADE Bleeding Risk Score used?
- Enter hematocrit, creatinine clearance, heart rate, systolic BP, and four categorical features; the tool returns the score, risk band, and estimated bleeding rate.
- What are the key clinical points for CRUSADE Bleeding Risk Score?
- For high-risk scores, prefer radial access and dose-adjusted antithrombotics to mitigate bleeding (original synthesis · not guideline verbatim). Creatinine clearance should be computed by Cockcroft-Gault for consistency with the derivation cohort. Bleeding risk must be weighed against ischemic risk rather than used to withhold indicated antithrombotic therapy outright.
- What are the limits and cautions when using CRUSADE Bleeding Risk Score?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is CRUSADE Bleeding Risk Score calculated in practice? Can you show a worked example?
- Inputs: Baseline hematocrit 38 %, Creatinine clearance CrCl 70 mL/min, Heart rate 80 bpm, Systolic blood pressure 130 mmHg, Female Yes, Signs of heart failure at admission Yes, Prior vascular disease Yes, Diabetes mellitus Yes → Result: CRUSADE score 48 pts（Bleeding risk group: High, In-hospital major bleeding (approx.): 11.9%） Inputs: Baseline hematocrit 38 %, Creatinine clearance CrCl 70 mL/min, Heart rate 80 bpm, Systolic blood pressure 130 mmHg, Female No, Signs of heart failure at admission No, Prior vascular disease No, Diabetes mellitus No → Result: CRUSADE score 21 pts（Bleeding risk group: Low, In-hospital major bleeding (approx.): 5.5%）