😮💨 Asthma Acute Exacerbation Management
This tool directs asthma exacerbation management by severity, framing bronchodilators, systemic steroids, controlled oxygen, and escalation.
IV theophylline/aminophylline is avoided for poor efficacy and high risk, and response is reassessed 1 hour after treatment. (original synthesis · not guideline verbatim)
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When to use
Use to triage and treat: mild-moderate in outpatient/community, severe in the ED with ipratropium and possible IV magnesium, and life-threatening in ED/ICU with ventilation readiness.
How it works
Core: repeated SABA + early systemic steroid + controlled oxygen (SpO₂ 93–95%). Severe adds ipratropium ± IV magnesium sulfate 2 g; life-threatening prepares for mechanical ventilation.
Key points
- IV theophylline/aminophylline is avoided for poor efficacy and high risk, and response is reassessed 1 hour after treatment. (original synthesis · not guideline verbatim)
- Systemic glucocorticoid is given early in severe exacerbations and a 5–7 day oral course in milder ones.
- Controller drugs are adjusted and follow-up arranged before discharge.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Exacerbation severity | Mild-moderate |
|---|
→Severity & dispositionMild-moderate: manageable in outpatient/community
- Triage：Mild-moderate: manageable in outpatient/community
- Bronchodilator：Repeated inhaled SABA (salbutamol 2–4 puffs, every 20 min for 1 h)
- Systemic steroid：Increase ICS (2–4×) or oral prednisone 40–50 mg (or 0.5–1 mg/kg), 5–7 day course
| Exacerbation severity | Life-threatening (drowsiness/coma/silent chest) |
|---|
→Severity & dispositionLife-threatening: ED/ICU, prepare for intubation and mechanical ventilation
- Triage：Life-threatening: ED/ICU, prepare for intubation and mechanical ventilation
- Bronchodilator：Continuous SABA + ipratropium nebulization
- Systemic steroid：Systemic glucocorticoid early: oral prednisone 40–50 mg or IV methylprednisolone
Frequently asked questions
- What is Asthma Acute Exacerbation Management?
- This tool directs asthma exacerbation management by severity, framing bronchodilators, systemic steroids, controlled oxygen, and escalation.
- How is Asthma Acute Exacerbation Management calculated? What is the core formula?
- Core: repeated SABA + early systemic steroid + controlled oxygen (SpO₂ 93–95%). Severe adds ipratropium ± IV magnesium sulfate 2 g; life-threatening prepares for mechanical ventilation.
- When is Asthma Acute Exacerbation Management used?
- Use to triage and treat: mild-moderate in outpatient/community, severe in the ED with ipratropium and possible IV magnesium, and life-threatening in ED/ICU with ventilation readiness.
- What are the key clinical points for Asthma Acute Exacerbation Management?
- IV theophylline/aminophylline is avoided for poor efficacy and high risk, and response is reassessed 1 hour after treatment. (original synthesis · not guideline verbatim) Systemic glucocorticoid is given early in severe exacerbations and a 5–7 day oral course in milder ones. Controller drugs are adjusted and follow-up arranged before discharge.
- What are the limits and cautions when using Asthma Acute Exacerbation Management?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Asthma Acute Exacerbation Management calculated in practice? Can you show a worked example?
- Inputs: Exacerbation severity Mild-moderate → Result: Severity & disposition Mild-moderate: manageable in outpatient/community（Triage: Mild-moderate: manageable in outpatient/community, Bronchodilator: Repeated inhaled SABA (salbutamol 2–4 puffs, every 20 min for 1 h), Systemic steroid: Increase ICS (2–4×) or oral prednisone 40–50 mg (or 0.5–1 mg/kg), 5–7 day course） Inputs: Exacerbation severity Life-threatening (drowsiness/coma/silent chest) → Result: Severity & disposition Life-threatening: ED/ICU, prepare for intubation and mechanical ventilation（Triage: Life-threatening: ED/ICU, prepare for intubation and mechanical ventilation, Bronchodilator: Continuous SABA + ipratropium nebulization, Systemic steroid: Systemic glucocorticoid early: oral prednisone 40–50 mg or IV methylprednisolone）