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🩸 Anemia Differential Interpretation

An MCV-based anemia differential with reticulocyte and iron-study interpretation. Browser-side reference that pairs with the RPI, TSAT and iron-deficit tools.

Anemia Differential Interpretation

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When to use

Frame the anemia workup by cell size and marrow response, then quantify with the dedicated calculators.

How it works

Microcytic < 80 fL, normocytic 80–100, macrocytic > 100 fL; reticulocyte production index > 2–3 = marrow response.

Key points

  • Microcytic: iron deficiency vs thalassaemia vs chronic disease.
  • Ferritin is an acute-phase reactant — falsely raised in inflammation.
  • Reticulocyte index separates haemolysis/blood loss from underproduction.
  • Macrocytosis: check B12/folate, alcohol/liver disease, hypothyroidism, MDS.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

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