Guideline decision tool · Radiology
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Liver LI-RADS (CT/MRI HCC) Category — free guideline decision tool

Compute the liver LI-RADS category (LR-3/4/5) from at-risk status, size and major features, with management. Instant, browser-side.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

At high risk for HCC (cirrhosis / chronic HBV / prior HCC)Yes
Lesion size15 mm
Non-rim arterial-phase hyper-enhancement (APHE)Yes
Non-peripheral washoutYes
Enhancing capsuleYes
Threshold growth (≥ 50% / ≤ 6 months)Yes

CategoryLR-5

  • CategoryLR-5 (definite HCC)
  • ReadNon-rim APHE present, size 15 mm, 3 additional major feature(s) (non-peripheral washout ✓, enhancing capsule ✓, threshold growth ✓)
  • ManagementDefinite HCC: non-invasive imaging diagnosis without biopsy; multidisciplinary HCC staging and treatment (resection/ablation/transplant/transarterial/systemic)
At high risk for HCC (cirrhosis / chronic HBV / prior HCC)No
Lesion size15 mm
Non-rim arterial-phase hyper-enhancement (APHE)No
Non-peripheral washoutNo
Enhancing capsuleNo
Threshold growth (≥ 50% / ≤ 6 months)No

ApplicabilityLI-RADS not applicable

  • Eligible populationDiagnostic CT/MRI LI-RADS applies only to patients at high risk for HCC: cirrhosis, chronic HBV, or current/prior HCC; not for age < 18, no risk factors, or cirrhosis from congenital hepatic fibrosis or vascular causes
  • AdviceEvaluate liver lesions in non-at-risk patients along a general liver-lesion diagnostic pathway
  • BasisACR LI-RADS v2018 CT/MRI diagnosis

Common questions

What is Liver LI-RADS (CT/MRI HCC) Category?

Compute the liver LI-RADS category (LR-3/4/5) from at-risk status, size and major features, with management. Instant, browser-side.

How is Liver LI-RADS (CT/MRI HCC) Category calculated? What is the core formula?

Major features — non-rim APHE, size, non-peripheral washout, enhancing capsule, threshold growth (≥ 50%/≤ 6 mo) — combine to LR-3/4/5. 10–19 mm + APHE + washout or threshold growth = LR-5.

When is Liver LI-RADS (CT/MRI HCC) Category used?

Categorise an observation on diagnostic CT/MRI in patients at high risk for HCC.

What are the key clinical points for Liver LI-RADS (CT/MRI HCC) Category?

LI-RADS applies only to patients at high risk for HCC (cirrhosis, chronic HBV, prior HCC). LR-5 allows non-invasive HCC diagnosis without biopsy. LR-M (non-HCC malignancy) and LR-TIV (venous invasion) are adjudicated separately. Capsule alone vs washout/threshold-growth changes the category in the 10–19 mm + APHE band.

What are the limits and cautions when using Liver LI-RADS (CT/MRI HCC) Category?

For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

How is Liver LI-RADS (CT/MRI HCC) Category calculated in practice? Can you show a worked example?

Inputs: At high risk for HCC (cirrhosis / chronic HBV / prior HCC) Yes, Lesion size 15 mm, Non-rim arterial-phase hyper-enhancement (APHE) Yes, Non-peripheral washout Yes, Enhancing capsule Yes, Threshold growth (≥ 50% / ≤ 6 months) Yes → Result: Category LR-5(Category: LR-5 (definite HCC), Read: Non-rim APHE present, size 15 mm, 3 additional major feature(s) (non-peripheral washout ✓, enhancing capsule ✓, threshold growth ✓), Management: Definite HCC: non-invasive imaging diagnosis without biopsy; multidisciplinary HCC staging and treatment (resection/ablation/transplant/transarterial/systemic)) Inputs: At high risk for HCC (cirrhosis / chronic HBV / prior HCC) No, Lesion size 15 mm, Non-rim arterial-phase hyper-enhancement (APHE) No, Non-peripheral washout No, Enhancing capsule No, Threshold growth (≥ 50% / ≤ 6 months) No → Result: Applicability LI-RADS not applicable(Eligible population: Diagnostic CT/MRI LI-RADS applies only to patients at high risk for HCC: cirrhosis, chronic HBV, or current/prior HCC; not for age < 18, no risk factors, or cirrhosis from congenital hepatic fibrosis or vascular causes, Advice: Evaluate liver lesions in non-at-risk patients along a general liver-lesion diagnostic pathway, Basis: ACR LI-RADS v2018 CT/MRI diagnosis)

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Compute the liver LI-RADS category (LR-3/4/5) from at-risk status, size and major features, with management. Instant, browser-side.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.