Guideline decision tool · Cardiology
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ACS GRACE Risk (framework) — free guideline decision tool

The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Show required inputs, risk bands and official linkShow

GRACEReference framework (use official calculator)

  • NatureThe GRACE score converts 8 variables into a mortality probability via a banded look-up / nonlinear regression (nomogram) with numerous band cut-points. To avoid fabricating the look-up, this tool lists the required 8 items and risk bands and provides the official calculator; it does not output fabricated scores/probabilities
  • 8 inputsAge, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac necrosis markers
  • In-hospital mortality bandsLow ≤ 108 (< 1%), intermediate 109–140 (1–3%), high > 140 (> 3%)

Common questions

What is ACS GRACE Risk (framework)?

The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.

How is ACS GRACE Risk (framework) calculated? What is the core formula?

Eight variables — age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac markers — mapped through a nomogram. In-hospital bands: low ≤108, intermediate 109–140, high >140.

When is ACS GRACE Risk (framework) used?

Use for NSTE-ACS risk stratification: a GRACE score > 140 (or intermediate-high risk) supports an early (< 24 h) invasive strategy, interpreted alongside guidelines and the clinical picture.

What are the key clinical points for ACS GRACE Risk (framework)?

The numerous band cut-points make the score unsuitable for on-platform reproduction; this page provides the inputs and risk bands and defers the exact score to the official calculator. (original synthesis · not guideline verbatim) In-hospital mortality bands: ≤108 (<1%), 109–140 (1–3%), >140 (>3%); 6-month: ≤88, 89–118, >118. GRACE is a guideline-endorsed tool for timing the invasive strategy in NSTE-ACS.

What are the limits and cautions when using ACS GRACE Risk (framework)?

For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

How is ACS GRACE Risk (framework) calculated in practice? Can you show a worked example?

Inputs: Show required inputs, risk bands and official link Show → Result: GRACE Reference framework (use official calculator)(Nature: The GRACE score converts 8 variables into a mortality probability via a banded look-up / nonlinear regression (nomogram) with numerous band cut-points. To avoid fabricating the look-up, this tool lists the required 8 items and risk bands and provides the official calculator; it does not output fabricated scores/probabilities, 8 inputs: Age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac necrosis markers, In-hospital mortality bands: Low ≤ 108 (< 1%), intermediate 109–140 (1–3%), high > 140 (> 3%))

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The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.