🫀 ACS GRACE Risk (framework)
The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.
The numerous band cut-points make the score unsuitable for on-platform reproduction; this page provides the inputs and risk bands and defers the exact score to the official calculator. (original synthesis · not guideline verbatim)
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When to use
Use for NSTE-ACS risk stratification: a GRACE score > 140 (or intermediate-high risk) supports an early (< 24 h) invasive strategy, interpreted alongside guidelines and the clinical picture.
How it works
Eight variables — age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac markers — mapped through a nomogram. In-hospital bands: low ≤108, intermediate 109–140, high >140.
Key points
- The numerous band cut-points make the score unsuitable for on-platform reproduction; this page provides the inputs and risk bands and defers the exact score to the official calculator. (original synthesis · not guideline verbatim)
- In-hospital mortality bands: ≤108 (<1%), 109–140 (1–3%), >140 (>3%); 6-month: ≤88, 89–118, >118.
- GRACE is a guideline-endorsed tool for timing the invasive strategy in NSTE-ACS.
References
- Granger CB, et al. Predictors of hospital mortality in the Global Registry of Acute Coronary Events (GRACE). Arch Intern Med 2003.
- GRACE ACS Risk Calculator (official).
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Show required inputs, risk bands and official link | Show |
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→GRACEReference framework (use official calculator)
- Nature：The GRACE score converts 8 variables into a mortality probability via a banded look-up / nonlinear regression (nomogram) with numerous band cut-points. To avoid fabricating the look-up, this tool lists the required 8 items and risk bands and provides the official calculator; it does not output fabricated scores/probabilities
- 8 inputs：Age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac necrosis markers
- In-hospital mortality bands：Low ≤ 108 (< 1%), intermediate 109–140 (1–3%), high > 140 (> 3%)
Frequently asked questions
- What is ACS GRACE Risk (framework)?
- The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.
- How is ACS GRACE Risk (framework) calculated? What is the core formula?
- Eight variables — age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac markers — mapped through a nomogram. In-hospital bands: low ≤108, intermediate 109–140, high >140.
- When is ACS GRACE Risk (framework) used?
- Use for NSTE-ACS risk stratification: a GRACE score > 140 (or intermediate-high risk) supports an early (< 24 h) invasive strategy, interpreted alongside guidelines and the clinical picture.
- What are the key clinical points for ACS GRACE Risk (framework)?
- The numerous band cut-points make the score unsuitable for on-platform reproduction; this page provides the inputs and risk bands and defers the exact score to the official calculator. (original synthesis · not guideline verbatim) In-hospital mortality bands: ≤108 (<1%), 109–140 (1–3%), >140 (>3%); 6-month: ≤88, 89–118, >118. GRACE is a guideline-endorsed tool for timing the invasive strategy in NSTE-ACS.
- What are the limits and cautions when using ACS GRACE Risk (framework)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is ACS GRACE Risk (framework) calculated in practice? Can you show a worked example?
- Inputs: Show required inputs, risk bands and official link Show → Result: GRACE Reference framework (use official calculator)（Nature: The GRACE score converts 8 variables into a mortality probability via a banded look-up / nonlinear regression (nomogram) with numerous band cut-points. To avoid fabricating the look-up, this tool lists the required 8 items and risk bands and provides the official calculator; it does not output fabricated scores/probabilities, 8 inputs: Age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac necrosis markers, In-hospital mortality bands: Low ≤ 108 (< 1%), intermediate 109–140 (1–3%), high > 140 (> 3%)）