Cerebral Perfusion Pressure (CPP) & ICP Targets — free guideline decision tool
Cerebral perfusion pressure (CPP = MAP − ICP) and intracranial-pressure targets in severe TBI and neurocritical care.
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Implements the decision logic from published clinical guidelines.
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No installation. Enter the patient's values and get a guideline recommendation instantly.
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Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Systolic BP SBP | 130 mmHg |
|---|---|
| Diastolic BP DBP | 70 mmHg |
| Intracranial pressure ICP | 18 mmHg |
→CPP72 mmHg
- Calculation：MAP = 90 mmHg (DBP + (SBP − DBP)/3); CPP = MAP − ICP = 90 − 18 = 72 mmHg
- CPP evaluation：Normal-high (> 70; if maintained by vasopressors, watch for ARDS)
- ICP evaluation：ICP 18 (≤ 20 broadly acceptable)
Common questions
What is Cerebral Perfusion Pressure (CPP) & ICP Targets?
Cerebral perfusion pressure (CPP = MAP − ICP) and intracranial-pressure targets in severe TBI and neurocritical care.
How is Cerebral Perfusion Pressure (CPP) & ICP Targets calculated? What is the core formula?
MAP = DBP + (SBP − DBP)/3; CPP = MAP − ICP; severe-TBI target CPP 60–70 mmHg; ICP > 22 mmHg triggers ICP-lowering therapy.
When is Cerebral Perfusion Pressure (CPP) & ICP Targets used?
Use to compute CPP from blood pressure and ICP and to check it against Brain Trauma Foundation targets.
What are the key clinical points for Cerebral Perfusion Pressure (CPP) & ICP Targets?
Maintaining CPP > 70 with vasopressors raises ARDS and volume-overload risk — CPP is an optimization target, not 'higher is better' (original synthesis · not guideline verbatim). Zero the arterial transducer at the tragus (≈ foramen of Monro) so MAP/CPP reflect cerebral, not cardiac, level. When autoregulation is impaired, cerebral blood flow follows CPP passively, making both hypo- and hypertension hazardous.
What are the limits and cautions when using Cerebral Perfusion Pressure (CPP) & ICP Targets?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Cerebral Perfusion Pressure (CPP) & ICP Targets calculated in practice? Can you show a worked example?
Inputs: Systolic BP SBP 130 mmHg, Diastolic BP DBP 70 mmHg, Intracranial pressure ICP 18 mmHg → Result: CPP 72 mmHg（Calculation: MAP = 90 mmHg (DBP + (SBP − DBP)/3); CPP = MAP − ICP = 90 − 18 = 72 mmHg, CPP evaluation: Normal-high (> 70; if maintained by vasopressors, watch for ARDS), ICP evaluation: ICP 18 (≤ 20 broadly acceptable)）
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Cerebral perfusion pressure (CPP = MAP − ICP) and intracranial-pressure targets in severe TBI and neurocritical care.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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