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🩸 Triglyceride-Glucose (TyG) Index

Estimate insulin resistance with the triglyceride-glucose (TyG) index.

Clinical takeaway

Derived from a standard lipid/glucose panel.

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When to use

Surrogate marker of insulin resistance from routine labs.

How it works

TyG = ln(fasting TG × fasting glucose / 2), mg/dL. Higher values = more insulin resistance.

Key points

  • Derived from a standard lipid/glucose panel.
  • Correlates with cardiometabolic risk.
  • Thresholds are population-specific.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Fasting triglycerides150 mg/dL
Fasting glucose100 mg/dL

TyG index8.92

  • Formulaln(TG × glucose / 2), mg/dL
  • NoteHigher values indicate greater insulin resistance; cut-offs vary by population (~4.5 often used).

Frequently asked questions

What is Triglyceride-Glucose (TyG) Index?
Estimate insulin resistance with the triglyceride-glucose (TyG) index.
How is Triglyceride-Glucose (TyG) Index calculated? What is the core formula?
TyG = ln(fasting TG × fasting glucose / 2), mg/dL. Higher values = more insulin resistance.
When is Triglyceride-Glucose (TyG) Index used?
Surrogate marker of insulin resistance from routine labs.
What are the key clinical points for Triglyceride-Glucose (TyG) Index?
Derived from a standard lipid/glucose panel. Correlates with cardiometabolic risk. Thresholds are population-specific.
What are the limits and cautions when using Triglyceride-Glucose (TyG) Index?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Triglyceride-Glucose (TyG) Index calculated in practice? Can you show a worked example?
Inputs: Fasting triglycerides 150 mg/dL, Fasting glucose 100 mg/dL → Result: TyG index 8.92(Formula: ln(TG × glucose / 2), mg/dL, Note: Higher values indicate greater insulin resistance; cut-offs vary by population (~4.5 often used).)

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