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🫁 Oxygenation Index (OI)

Calculate the oxygenation index (OI) for ventilated patients, central to paediatric ARDS grading.

Clinical takeaway

Accounts for mean airway pressure, unlike the P/F ratio.

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When to use

Grade oxygenation severity incorporating ventilator support.

How it works

OI = (FiO₂% × mean airway pressure) / PaO₂. PALICC: 4–8 mild, 8–16 moderate, ≥ 16 severe.

Key points

  • Accounts for mean airway pressure, unlike the P/F ratio.
  • Higher OI = worse oxygenation.
  • Oxygen saturation index (OSI) is a non-invasive analogue.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

FiO₂0.6 fraction
Mean airway pressure15 cmH₂O
PaO₂70 mmHg

OI12.9

  • SeverityModerate
  • FormulaOI = (FiO₂% × mean airway pressure) / PaO₂

Frequently asked questions

What is Oxygenation Index (OI)?
Calculate the oxygenation index (OI) for ventilated patients, central to paediatric ARDS grading.
How is Oxygenation Index (OI) calculated? What is the core formula?
OI = (FiO₂% × mean airway pressure) / PaO₂. PALICC: 4–8 mild, 8–16 moderate, ≥ 16 severe.
When is Oxygenation Index (OI) used?
Grade oxygenation severity incorporating ventilator support.
What are the key clinical points for Oxygenation Index (OI)?
Accounts for mean airway pressure, unlike the P/F ratio. Higher OI = worse oxygenation. Oxygen saturation index (OSI) is a non-invasive analogue.
What are the limits and cautions when using Oxygenation Index (OI)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Oxygenation Index (OI) calculated in practice? Can you show a worked example?
Inputs: FiO₂ 0.6 fraction, Mean airway pressure 15 cmH₂O, PaO₂ 70 mmHg → Result: OI 12.9(Severity: Moderate, Formula: OI = (FiO₂% × mean airway pressure) / PaO₂)

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