🧪 HOMA-β (Beta-cell Function)
Estimate beta-cell function with HOMA-β from fasting glucose and insulin.
Clinical takeaway
A steady-state model, not a diagnostic test.
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When to use
Research/epidemiological assessment of insulin secretion.
How it works
HOMA-β = 20 × insulin / (glucose − 3.5), glucose in mmol/L. Normal ≈ 100%.
Key points
- A steady-state model, not a diagnostic test.
- Interpret against a local reference population.
- Pair with HOMA-IR for a fuller picture.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Fasting insulin | 10 µU/mL |
|---|---|
| Fasting glucose | 5 mmol/L |
→HOMA-β133%
- Formula：20 × insulin / (glucose − 3.5)
- Reference：Normal ≈ 100% (population-dependent)
Frequently asked questions
- What is HOMA-β (Beta-cell Function)?
- Estimate beta-cell function with HOMA-β from fasting glucose and insulin.
- How is HOMA-β (Beta-cell Function) calculated? What is the core formula?
- HOMA-β = 20 × insulin / (glucose − 3.5), glucose in mmol/L. Normal ≈ 100%.
- When is HOMA-β (Beta-cell Function) used?
- Research/epidemiological assessment of insulin secretion.
- What are the key clinical points for HOMA-β (Beta-cell Function)?
- A steady-state model, not a diagnostic test. Interpret against a local reference population. Pair with HOMA-IR for a fuller picture.
- What are the limits and cautions when using HOMA-β (Beta-cell Function)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is HOMA-β (Beta-cell Function) calculated in practice? Can you show a worked example?
- Inputs: Fasting insulin 10 µU/mL, Fasting glucose 5 mmol/L → Result: HOMA-β 133 %（Formula: 20 × insulin / (glucose − 3.5), Reference: Normal ≈ 100% (population-dependent)）