💉 Glucose Infusion Rate (GIR)
Glucose infusion rate (GIR) expresses intravenous dextrose delivery in mg/kg/min, the key parameter for neonatal and infant glycemic management.
Neonatal maintenance typically needs ~4–8 mg/kg/min, while persistent hypoglycemia may require 8–12 or more, and a sustained requirement above ~12–15 raises suspicion of hyperinsulinism (original synthesis · not guideline verbatim).
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When to use
Enter infusion rate (mL/h), dextrose concentration (%), and weight (kg); the tool returns GIR in mg/kg/min.
How it works
GIR (mg/kg/min) = rate (mL/h) × concentration (%) / (6 × weight kg).
Key points
- Neonatal maintenance typically needs ~4–8 mg/kg/min, while persistent hypoglycemia may require 8–12 or more, and a sustained requirement above ~12–15 raises suspicion of hyperinsulinism (original synthesis · not guideline verbatim).
- Peripheral lines generally tolerate no more than 12.5% dextrose; higher concentrations need central venous access.
- Always titrate to bedside glucose monitoring and recalculate whenever rate, concentration, or weight changes.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Infusion rate | 12 mL/h |
|---|---|
| Glucose concentration | 10 % |
| Weight | 3 kg |
→GIR6.7mg/kg/min
- Formula：rate(mL/h) × concentration(%) / (6 × weight kg)
Frequently asked questions
- What is Glucose Infusion Rate (GIR)?
- Glucose infusion rate (GIR) expresses intravenous dextrose delivery in mg/kg/min, the key parameter for neonatal and infant glycemic management.
- How is Glucose Infusion Rate (GIR) calculated? What is the core formula?
- GIR (mg/kg/min) = rate (mL/h) × concentration (%) / (6 × weight kg).
- When is Glucose Infusion Rate (GIR) used?
- Enter infusion rate (mL/h), dextrose concentration (%), and weight (kg); the tool returns GIR in mg/kg/min.
- What are the key clinical points for Glucose Infusion Rate (GIR)?
- Neonatal maintenance typically needs ~4–8 mg/kg/min, while persistent hypoglycemia may require 8–12 or more, and a sustained requirement above ~12–15 raises suspicion of hyperinsulinism (original synthesis · not guideline verbatim). Peripheral lines generally tolerate no more than 12.5% dextrose; higher concentrations need central venous access. Always titrate to bedside glucose monitoring and recalculate whenever rate, concentration, or weight changes.
- What are the limits and cautions when using Glucose Infusion Rate (GIR)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Glucose Infusion Rate (GIR) calculated in practice? Can you show a worked example?
- Inputs: Infusion rate 12 mL/h, Glucose concentration 10 %, Weight 3 kg → Result: GIR 6.7 mg/kg/min（Formula: rate(mL/h) × concentration(%) / (6 × weight kg)）