💉 Glucose Infusion Rate (GIR)

When to use

Enter infusion rate (mL/h), dextrose concentration (%), and weight (kg); the tool returns GIR in mg/kg/min.

How it works

GIR (mg/kg/min) = rate (mL/h) × concentration (%) / (6 × weight kg).

Key points

• Neonatal maintenance typically needs ~4–8 mg/kg/min, while persistent hypoglycemia may require 8–12 or more, and a sustained requirement above ~12–15 raises suspicion of hyperinsulinism (original synthesis · not guideline verbatim).
• Peripheral lines generally tolerate no more than 12.5% dextrose; higher concentrations need central venous access.
• Always titrate to bedside glucose monitoring and recalculate whenever rate, concentration, or weight changes.

References

• Cornblath M, et al. Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds. Pediatrics. 2000;105(5):1141-1145.

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