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💧 Effusion / CSF Interpretation

Interpret pleural fluid by Light's criteria, ascites by SAAG and CSF by the cell/protein/glucose pattern. Browser-side reference.

Clinical takeaway

After diuresis, a serum-fluid albumin gradient > 12 g/L suggests a pseudoexudate.

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When to use

Separate exudate from transudate, identify portal hypertension and give a first read of CSF; pairs with the Light and CSF-correction tools.

How it works

Light's exudate (any): fluid/serum protein > 0.5, fluid/serum LDH > 0.6, fluid LDH > ⅔ ULN. SAAG ≥ 11 g/L = portal hypertension.

Key points

  • After diuresis, a serum-fluid albumin gradient > 12 g/L suggests a pseudoexudate.
  • SAAG ≥ 11 g/L points to portal hypertension.
  • Bacterial CSF: neutrophils, high protein, low glucose (CSF/blood < 0.4).
  • Correct CSF WBC for a traumatic tap.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ViewPleural — Light's

InterpretationPleural effusion (Light's criteria)

  • Exudate (any one)Fluid/serum protein > 0.5, fluid/serum LDH > 0.6, fluid LDH > 2/3 of the upper normal limit (see 'Light's criteria')
  • TransudateNone met: heart failure / cirrhosis / nephrotic syndrome
  • PseudoexudateAfter diuresis → serum-to-fluid albumin gradient > 12 g/L suggests it is really a transudate
ViewCSF

InterpretationCerebrospinal fluid (CSF)

  • BacterialNeutrophils ↑↑, protein ↑↑, glucose ↓ (CSF/blood glucose < 0.4), pressure ↑
  • ViralLymphocytes ↑, protein normal/mildly ↑, glucose normal
  • TB/fungalLymphocytes ↑, protein ↑↑, glucose ↓

Frequently asked questions

What is Effusion / CSF Interpretation?
Interpret pleural fluid by Light's criteria, ascites by SAAG and CSF by the cell/protein/glucose pattern. Browser-side reference.
How is Effusion / CSF Interpretation calculated? What is the core formula?
Light's exudate (any): fluid/serum protein > 0.5, fluid/serum LDH > 0.6, fluid LDH > ⅔ ULN. SAAG ≥ 11 g/L = portal hypertension.
When is Effusion / CSF Interpretation used?
Separate exudate from transudate, identify portal hypertension and give a first read of CSF; pairs with the Light and CSF-correction tools.
What are the key clinical points for Effusion / CSF Interpretation?
After diuresis, a serum-fluid albumin gradient > 12 g/L suggests a pseudoexudate. SAAG ≥ 11 g/L points to portal hypertension. Bacterial CSF: neutrophils, high protein, low glucose (CSF/blood < 0.4). Correct CSF WBC for a traumatic tap.
What are the limits and cautions when using Effusion / CSF Interpretation?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Effusion / CSF Interpretation calculated in practice? Can you show a worked example?
Inputs: View Pleural — Light's → Result: Interpretation Pleural effusion (Light's criteria)(Exudate (any one): Fluid/serum protein > 0.5, fluid/serum LDH > 0.6, fluid LDH > 2/3 of the upper normal limit (see 'Light's criteria'), Transudate: None met: heart failure / cirrhosis / nephrotic syndrome, Pseudoexudate: After diuresis → serum-to-fluid albumin gradient > 12 g/L suggests it is really a transudate) Inputs: View CSF → Result: Interpretation Cerebrospinal fluid (CSF)(Bacterial: Neutrophils ↑↑, protein ↑↑, glucose ↓ (CSF/blood glucose < 0.4), pressure ↑, Viral: Lymphocytes ↑, protein normal/mildly ↑, glucose normal, TB/fungal: Lymphocytes ↑, protein ↑↑, glucose ↓)

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