🫀 Oxygen Delivery (DO₂)
Calculate global oxygen delivery (DO₂) from cardiac output and oxygen content.
Clinical takeaway
Integrates cardiac output and oxygen content.
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When to use
Assess adequacy of oxygen supply in critical illness.
How it works
DO₂ = CO × CaO₂ × 10, with CaO₂ = 1.34·Hb·SaO₂ + 0.0031·PaO₂. Normal ~ 950–1150 mL/min.
Key points
- Integrates cardiac output and oxygen content.
- Below a critical threshold, consumption becomes supply-dependent.
- Often indexed to body surface area (DO₂I).
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Cardiac output | 5 L/min |
|---|---|
| Haemoglobin | 15 g/dL |
| SaO₂ | 98 % |
| PaO₂ (optional) | 100 mmHg |
→DO₂1000mL O₂/min
- CaO₂：20.0 mL/dL
- Formula：CO × CaO₂ × 10
- Normal：~ 950–1150 mL/min (index ~500–600 mL/min/m²)
Frequently asked questions
- What is Oxygen Delivery (DO₂)?
- Calculate global oxygen delivery (DO₂) from cardiac output and oxygen content.
- How is Oxygen Delivery (DO₂) calculated? What is the core formula?
- DO₂ = CO × CaO₂ × 10, with CaO₂ = 1.34·Hb·SaO₂ + 0.0031·PaO₂. Normal ~ 950–1150 mL/min.
- When is Oxygen Delivery (DO₂) used?
- Assess adequacy of oxygen supply in critical illness.
- What are the key clinical points for Oxygen Delivery (DO₂)?
- Integrates cardiac output and oxygen content. Below a critical threshold, consumption becomes supply-dependent. Often indexed to body surface area (DO₂I).
- What are the limits and cautions when using Oxygen Delivery (DO₂)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Oxygen Delivery (DO₂) calculated in practice? Can you show a worked example?
- Inputs: Cardiac output 5 L/min, Haemoglobin 15 g/dL, SaO₂ 98 %, PaO₂ (optional) 100 mmHg → Result: DO₂ 1000 mL O₂/min（CaO₂: 20.0 mL/dL, Formula: CO × CaO₂ × 10, Normal: ~ 950–1150 mL/min (index ~500–600 mL/min/m²)）