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🧂 Hyperglycemia-Corrected Sodium

Correct measured sodium for hyperglycemia to reveal the true sodium status.

Clinical takeaway

Hyperglycemia causes dilutional (pseudo) hyponatremia.

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When to use

Avoid misreading dilutional hyponatremia in hyperglycemic patients.

How it works

Katz: Na + 0.016 × (glucose mg/dL − 100). Hillier: Na + 0.024 × (glucose mg/dL − 100), closer at severe hyperglycemia.

Key points

  • Hyperglycemia causes dilutional (pseudo) hyponatremia.
  • The corrected value predicts sodium once glucose is normalized.
  • Recheck electrolytes during glucose correction.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Measured sodium130 mmol/L
Glucose30 mmol/L

Corrected Na (Katz)137.0mmol/L

  • Corrected Na (Hillier)140.6 mmol/L
  • Measured Na130.0 mmol/L

Frequently asked questions

What is Hyperglycemia-Corrected Sodium?
Correct measured sodium for hyperglycemia to reveal the true sodium status.
How is Hyperglycemia-Corrected Sodium calculated? What is the core formula?
Katz: Na + 0.016 × (glucose mg/dL − 100). Hillier: Na + 0.024 × (glucose mg/dL − 100), closer at severe hyperglycemia.
When is Hyperglycemia-Corrected Sodium used?
Avoid misreading dilutional hyponatremia in hyperglycemic patients.
What are the key clinical points for Hyperglycemia-Corrected Sodium?
Hyperglycemia causes dilutional (pseudo) hyponatremia. The corrected value predicts sodium once glucose is normalized. Recheck electrolytes during glucose correction.
What are the limits and cautions when using Hyperglycemia-Corrected Sodium?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Hyperglycemia-Corrected Sodium calculated in practice? Can you show a worked example?
Inputs: Measured sodium 130 mmol/L, Glucose 30 mmol/L → Result: Corrected Na (Katz) 137.0 mmol/L(Corrected Na (Hillier): 140.6 mmol/L, Measured Na: 130.0 mmol/L)

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