❤️ ASCVD 10-Year Risk (Pooled Cohort Equations)
Estimate the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) with the 2013 ACC/AHA Pooled Cohort Equations. Free, instant, browser-side — no data leaves your device.
Clinical takeaway
A statin is generally considered at ≥ 7.5% 10-year risk, with shared decision-making and risk-enhancing factors.
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When to use
Primary-prevention risk assessment in adults aged 40–79 without established ASCVD, to guide statin and risk-factor decisions.
How it works
Race- and sex-specific Pooled Cohort Equations using age, total and HDL cholesterol, systolic BP (treated/untreated), smoking and diabetes. Strata: < 5% low, 5–7.5% borderline, 7.5–20% intermediate, ≥ 20% high.
Key points
- A statin is generally considered at ≥ 7.5% 10-year risk, with shared decision-making and risk-enhancing factors.
- The PCE were derived in US White and African-American cohorts and often over-estimate risk in Asian and some other populations.
- Use only for primary prevention (no established ASCVD); cholesterol entered in mmol/L is converted internally to mg/dL.
- Consider a locally validated model (China-PAR, SCORE2) where available.
References
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Frequently asked questions
- What is ASCVD 10-Year Risk (Pooled Cohort Equations)?
- Estimate the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) with the 2013 ACC/AHA Pooled Cohort Equations. Free, instant, browser-side — no data leaves your device.
- How is ASCVD 10-Year Risk (Pooled Cohort Equations) calculated? What is the core formula?
- Race- and sex-specific Pooled Cohort Equations using age, total and HDL cholesterol, systolic BP (treated/untreated), smoking and diabetes. Strata: < 5% low, 5–7.5% borderline, 7.5–20% intermediate, ≥ 20% high.
- When is ASCVD 10-Year Risk (Pooled Cohort Equations) used?
- Primary-prevention risk assessment in adults aged 40–79 without established ASCVD, to guide statin and risk-factor decisions.
- What are the key clinical points for ASCVD 10-Year Risk (Pooled Cohort Equations)?
- A statin is generally considered at ≥ 7.5% 10-year risk, with shared decision-making and risk-enhancing factors. The PCE were derived in US White and African-American cohorts and often over-estimate risk in Asian and some other populations. Use only for primary prevention (no established ASCVD); cholesterol entered in mmol/L is converted internally to mg/dL. Consider a locally validated model (China-PAR, SCORE2) where available.
- What are the limits and cautions when using ASCVD 10-Year Risk (Pooled Cohort Equations)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.