Prediction-Model Sample Size (Riley) — free, runs in your browser
Minimum sample size to develop a clinical prediction model (binary): Riley 2019 three criteria (shrinkage S=0.9, Nagelkerke R² difference ≤0.05, outcome… Computed in your browser — no data uploaded.
Open free tool →Runs in your browser
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Export charts as SVG vector or HD/UHD PNG suitable for journal submission.
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Common questions
When should I use Prediction-Model Sample Size?
Minimum sample size to develop a clinical prediction model (binary): Riley 2019 three criteria (shrinkage S=0.9, Nagelkerke R² difference ≤0.05, outcome-risk precision), taking the maximum; gives required n, events and events-per-parameter (EPP). …
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All calculations run entirely in your browser. No data is sent to any server. You can even use the tool offline after the page loads.
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Minimum sample size to develop a clinical prediction model (binary): Riley 2019 three criteria (shrinkage S=0.9, Nagelkerke R² difference ≤0.05, outcome… Computed in your browser — no data uploaded.
Open free tool →Free to use. No account required. No data uploaded.