Guideline decision tool · Neonatology
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Premature Infant Pain Profile (PIPP) — free guideline decision tool

The Premature Infant Pain Profile (PIPP) is a validated multidimensional pain scale for preterm and term newborns, combining contextual, physiologic and facial indicators.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Common questions

What does Premature Infant Pain Profile (PIPP) do?

Use to assess acute or procedural pain in preterm infants and to guide and reassess analgesia.

How is the result calculated?

Seven items — gestational age, behavioral state, maximum heart-rate increase, maximum desaturation, brow bulge, eye squeeze, nasolabial furrow — each 0–3, total 0–21: ≤ 6 no/minimal, 7–12 moderate, > 12 severe.

Is this a substitute for clinical judgement?

No. All results are decision-support only, for licensed clinicians. They must be individualized to the whole patient and the latest guideline version.

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Run Premature Infant Pain Profile (PIPP) now

The Premature Infant Pain Profile (PIPP) is a validated multidimensional pain scale for preterm and term newborns, combining contextual, physiologic and facial indicators.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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Related guideline tools

For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.