Prostate PI-RADS v2.1 Score — free guideline decision tool
Compute the prostate PI-RADS v2.1 assessment category by zone using the dominant sequence and upgrade rules, with management. Instant, browser-side.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Lesion zone | Peripheral zone PZ (DWI dominant) |
|---|---|
| DWI/ADC score | 1 |
| T2WI score | 1 |
| DCE dynamic enhancement | Positive (focal early enhancement at the suspicious lesion) |
→ScorePI-RADS 1
- Score：PI-RADS 1 (clinically significant cancer detection rate ~3%)
- Basis：PZ is DWI-dominant; DWI = 1 → PI-RADS 1
- Management：Clinically significant cancer highly unlikely: generally no biopsy; follow PSA/clinical
| Lesion zone | Transition zone TZ (T2 dominant) |
|---|---|
| DWI/ADC score | 5 |
| T2WI score | 5 |
| DCE dynamic enhancement | Negative |
→ScorePI-RADS 5
- Score：PI-RADS 5 (clinically significant cancer detection rate ~83%)
- Basis：TZ is T2-dominant; T2 = 5 → PI-RADS 5
- Management：Clinically significant cancer highly likely: MRI-targeted biopsy recommended
Common questions
What is Prostate PI-RADS v2.1 Score?
Compute the prostate PI-RADS v2.1 assessment category by zone using the dominant sequence and upgrade rules, with management. Instant, browser-side.
How is Prostate PI-RADS v2.1 Score calculated? What is the core formula?
PZ is DWI-dominant (DWI = 3 upgrades to 4 with positive DCE); TZ is T2-dominant (T2 = 2 + DWI ≥ 4 → 3, T2 = 3 + DWI = 5 → 4). Categories 1–5.
When is Prostate PI-RADS v2.1 Score used?
Score a prostate mpMRI lesion and decide on MRI-targeted biopsy.
What are the key clinical points for Prostate PI-RADS v2.1 Score?
DCE only arbitrates the peripheral-zone DWI-3 lesion. PI-RADS 1–2 carry low likelihood of clinically significant cancer. PI-RADS 3 is equivocal — PSA density (≥ 0.15) favours biopsy. PI-RADS 4–5 warrant MRI-targeted biopsy.
What are the limits and cautions when using Prostate PI-RADS v2.1 Score?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Prostate PI-RADS v2.1 Score calculated in practice? Can you show a worked example?
Inputs: Lesion zone Peripheral zone PZ (DWI dominant), DWI/ADC score 1, T2WI score 1, DCE dynamic enhancement Positive (focal early enhancement at the suspicious lesion) → Result: Score PI-RADS 1（Score: PI-RADS 1 (clinically significant cancer detection rate ~3%), Basis: PZ is DWI-dominant; DWI = 1 → PI-RADS 1, Management: Clinically significant cancer highly unlikely: generally no biopsy; follow PSA/clinical） Inputs: Lesion zone Transition zone TZ (T2 dominant), DWI/ADC score 5, T2WI score 5, DCE dynamic enhancement Negative → Result: Score PI-RADS 5（Score: PI-RADS 5 (clinically significant cancer detection rate ~83%), Basis: TZ is T2-dominant; T2 = 5 → PI-RADS 5, Management: Clinically significant cancer highly likely: MRI-targeted biopsy recommended）
Run Prostate PI-RADS v2.1 Score now
Compute the prostate PI-RADS v2.1 assessment category by zone using the dominant sequence and upgrade rules, with management. Instant, browser-side.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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