Guideline decision tool · Hepatology
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Hepatitis C Antiviral Treatment (DAA) — free guideline decision tool

This tool gives the HCV direct-acting-antiviral regimen direction by cirrhosis status and pregnancy, with pre-treatment assessment and the SVR12 endpoint.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Common questions

What does Hepatitis C Antiviral Treatment (DAA) do?

Use to choose a pangenotypic regimen in non-cirrhotic/compensated disease, a specialist SOF/VEL + RBV regimen in decompensation, and to defer therapy in pregnancy.

How is the result calculated?

No cirrhosis/compensated → SOF/VEL 12 weeks or GLE/PIB 8 weeks. Decompensated → protease inhibitors contraindicated, SOF/VEL + RBV 12 weeks. Pregnant → defer. Endpoint SVR12.

Is this a substitute for clinical judgement?

No. All results are decision-support only, for licensed clinicians. They must be individualized to the whole patient and the latest guideline version.

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Run Hepatitis C Antiviral Treatment (DAA) now

This tool gives the HCV direct-acting-antiviral regimen direction by cirrhosis status and pregnancy, with pre-treatment assessment and the SVR12 endpoint.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.